Universität zu Köln
Cluster of Excellence: Cellular Stress Responses in Aging-Associated Diseases

Björn Schumacher, Ph.D.

Publications

 

Reinhardt HC, Schumacher B

The p53 network: Cellular and systemic DNA damage responses in aging and cancer

Trends Genet. 2012 Jan 19.

 

Schwer B, Schumacher B, Lombard DB, Xiao C, Kurtev MV, Gao J, Schneider JI, Chai H, Bronson RT, Tsai LH, Deng CX, Alt FW.

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.

Proc Natl Acad Sci U S A. 2010 Nov 22.

 

Motameny S, Wolters S, Nürnberg P, Schumacher B.

Next Generation Sequencing of miRNAs – Strategies, Resources and Methods.

Genes. 2010; 1(1):70-84.

 

Lans H, Marteijn JA, Schumacher B, Hoeijmakers JH, Jansen G, Vermeulen W.

Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.

PLoS Genet. 2010 May 6;6:e1000941.

 

Schumacher B

Transcription-blocking DNA damage in aging: a mechanism for hormesis.

Bioessays. 2009 Dec;31(12):1347-56.

 

Garinis GA, Schumacher B

Transcription-blocking DNA damage in aging and longevity.

Cell Cycle. 2009 Jul 20;8(14).

 

Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LHF, van der Horst GTJ, Brüning JC, Niessen CM, Hoeijmakers JHJ and Schumacher B

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.

Nature Cell Biol. 2009 May;11(5):604-15.

 

Schumacher B, Hoeijmakers JH, Garinis GA

Sealing the gap between nuclear DNA damage and longevity.

Mol Cell Endocrinol. 2009 Feb 5;299(1):112-7. Epub 2008 Nov 5.

 

Schumacher B, van der Pluijm I, Moorhouse MJ, Rasile Robinson A, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van Ijcken W, Bartke A, Spindler SR, Hoeijmakers JHJ, van der Horst GTJ and Garinis GA
Delayed and accelerated aging share common longevity assurance mechanisms.
PLoS Genet. 2008 Aug 15;4(8):e1000161.

 

Greiss S#, Schumacher B#, Grandien K, Rothblatt J and Gartner A
Transcriptional profiling in C. elegans cep-1/p53 dependent apoptosis as a primordial function of p53 like genes.
BMC Genomics. 2008 Jul 15;9(1):334.

 

Schumacher B, Garinis G, Hoeijmakers J
Age to survive: DNA damage and aging.
Trends Genet. 2008 Feb;24(2):77-85.

 

Garinis G, Patil C, Schumacher B
"The molecular basis of aging": the Boehringer Ingelheim Fonds 95th International Titisee Conference.
Mech Ageing Dev. 2007 Jul-Aug;128(7-8):469-75.

 

Schumacher B & Gartner A
Translational regulation of p53 as a potential tumor therapy target.
Future Oncology, 2006;2(1):145-153.

 

Schumacher B, Hanazawa M, Lee M, Nayak S, Volkmann K, Hofmann R, Hengartner M, Schedl T, Gartner A
Translational Repression of C. elegans p53 by GLD-1 regulates DNA damage induced apoptosis
Cell, 11 February 2005; 120: 357-368.

 

Schumacher B, Schertel C, Wittenburg N, Tuck S, Mitani S, Gartner A, Conradt B, Shaham S
C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.
Cell Death Differ. 2005 Feb;12(2):153-61.

 

Schumacher B, Alpi A, Gartner A
Cell cycle: check for asynchrony.
Curr Biol. 2003 Jul 15;13(14):R560-2.

 

Gartner A, Alpi A, Schumacher B
Promgrammed cell death in C. elegans.
Genetics of Apoptosis, Grimm S (ed.), BIOS Scientific Publishers Limited, 2003, 155-175

 

Schumacher B, Hofmann K, Boulton S, Gartner A

The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis.
Curr Biol. 2001 Oct 30;11(21):1722-7.