Dr. Susan Parvaresch

Special interests:

Purification of membrane proteins
  • Purification of human placenta insulin receptor, baculovirus expressed insulin receptor kinase and GST-tagged kinases
  • Cloning, expression and purification of recombinant proteins
General research interest:
  • Mechanism of kinase activation
  • Studies of dual kinase activity
Selected Publications:
  • Dimerization-induced activation of soluble insulin/IGF-1 receptor kinases: An alternative mechanism of activation.
    Baer, K., Al-Hasani, H., Parvaresch, S., Corona, T., Rufer, A., Noelle, V., Bergschneider, E., and Klein, H.W. (2001)
    Biochemistry 40, 14268-14278 Medline
  • Identification of Ser 1275 and Ser 1309 as Autophosphorylation Sites of the Human Insulin Receptor in Intact Cells.
    Tennagels, N., Telting D, Parvaresch, S. Maassen, J.A., and Klein, H.W.
    Biochemical and Biophysical Research Communications 282, 387-393 (2001)
  • Recombinant peptide substrates of the insulin receptor.
    Noelle, V., Klein, E., Leven, O., Müller, J., Parvaresch, S., and Klein, H.W. (1996)
    Biol. Chem. Hoppe-Seyler 377, S154
  • The dual kinase activity of the insulin receptor in respect to auto- and substrate phosphorylation.
    Tennagels, N., Magg, C., Noelle, V., Parvaresch, S., Müller-Wieland, D., and Klein, H.W. (1997)
    Diabetes 46, suppl. 1, 384

1. OG Tel 470 - 6237 Email acc08@mail1.rrz.uni-koeln.de