Arabidopsis AUX1 gene: A permease-like regulator of root gravitropism
Bennett MJ, Marchant A, Green HG, May ST, Ward SP, Millner PA, Walker AR, Schulz B, Feldmann KA
SCIENCE

273: (5277) 948-950 AUG 16 1996


Abstract:
The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid-like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.

KeyWords Plus:
THALIANA, ACID, TRANSPORT, EXPRESSION, PROTEINS, SPECIFICITY, RESISTANCE, RESPONSES, MEMBRANE, MUTANTS

Addresses:
Bennett MJ, UNIV WARWICK, DEPT BIOL SCI, COVENTRY CV4 7AL, W MIDLANDS, ENGLAND.
UNIV LEEDS, DEPT BIOCHEM & MOL BIOL, LEEDS LS2 9JT, W YORKSHIRE, ENGLAND.
UNIV CAMBRIDGE, DEPT PLANT SCI, CAMBRIDGE CB2 1TN, ENGLAND.
UNIV ARIZONA, DEPT PLANT SCI, TUCSON, AZ 85721.

Publisher:
AMER ASSOC ADVANCEMENT SCIENCE, WASHINGTON

IDS Number:
VC670

ISSN:
0036-8075