Arabidopsis AUX1 gene: A permease-like
regulator of root gravitropism
Bennett MJ, Marchant A, Green HG, May ST, Ward SP, Millner PA, Walker AR, Schulz B, Feldmann KA
273: (5277) 948-950 AUG 16 1996
The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid-like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.
THALIANA, ACID, TRANSPORT, EXPRESSION, PROTEINS, SPECIFICITY, RESISTANCE, RESPONSES, MEMBRANE, MUTANTS
Bennett MJ, UNIV WARWICK, DEPT BIOL SCI, COVENTRY CV4 7AL, W MIDLANDS, ENGLAND.
UNIV LEEDS, DEPT BIOCHEM & MOL BIOL, LEEDS LS2 9JT, W YORKSHIRE, ENGLAND.
UNIV CAMBRIDGE, DEPT PLANT SCI, CAMBRIDGE CB2 1TN, ENGLAND.
UNIV ARIZONA, DEPT PLANT SCI, TUCSON, AZ 85721.
AMER ASSOC ADVANCEMENT SCIENCE, WASHINGTON