Matias, A.C., Ramos, P.C., and Dohmen, R.J. (2023). Hsp70 and Hsp110 chaperones promote early steps of proteasome assembly. Biomolecules 13, 11. doi: 10.3390/biom13010011. full text
Halwas, K.; Döring, L.-M.; Oehlert, F.V.; Dohmen, R.J. (2022). Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in Saccharomyces cerevisiae. Int. J. Mol. Sci. 23, 12972. https://doi.org/10.3390/ ijms23211297. full text
Zimmermann, J., Ramos, P.C., and Dohmen, R.J. (2022). MM Interaction with the Assembly Chaperone Ump1 Promotes Incorporation of the β7 Subunit into Half-Proteasome Precursor Complexes Driving Their Dimerization. Biomolecules. 2022, 12, 253. doi: 10.3390/biom12020253. full text
Meinhardt, A., Ramos, P.C., Dohmen, R.J., Lucas. N., Lee-Kirsch, M.A., Becker, B., de Laffolie, J., Cunha, T., Niehues, T., Salzer, U., Yoshimi, A., Erlacher, M., Peters, A.M.J., Ehl, S., Strahm, B., Speckmann, C. (2021). Curative Treatment of POMP-Related Autoinflammation and Immune Dysregulation (PRAID) by Hematopoietic Stem Cell Transplantation. J Clin Immunol. 41,1664-1667. doi: 10.1007/s10875-021-01067-7. full text
Pradhan, A.K., Kandasamy, G., Chatterjee, U., Bharadwaj, A., Mathew, S.J., Dohmen, R.J., Palanimurugan, R. (2021). Ribosome-associated quality control mediates degradation of the premature translation termination product Orf1p of ODC antizyme mRNA. (2021). FEBS Lett. 595, 2015-2033. doi: 10.1002/1873-3468.14147. full text
Schuster, R., Anton, V., Simoes, T., Altin, S., den Brave, F., Hermanns, T., Hospenthal, M., Komander, D., Dittmar, G., Dohmen, R.J., Escobar-Henriques, M. (2019). Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation. Life Sci Alliance. 3, e201900476. doi: 10.26508/lsa.201900476. full text
Sriramachandran, A.M., Meyer-Teschendorf, K., Pabst, S., Urich, H.D., Gehring, N.H., Hofmann, K., Praefcke, G.J.K., and Dohmen, R.J. (2019). Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chains. Nature Commun. DOI: 10.1038/s41467-019-11549-3. full text
Pabst, S., Döring, L.M., and Dohmen, R.J. (2019). Methods to study SUMO dynamics in yeast. Methods Enzymol. 618 :187-210. full text
Palanimurugan, R., Gödderz, D., Kurian, L., and Dohmen, R.J. (2018). Analysis of Cotranslational Polyamine Sensing During Decoding of ODC Antizyme mRNA. Methods Mol. Biol. 2018;1694:309-323. doi: 10.1007/978-1-4939-7398-9_26.
Eckhoff, J., and Dohmen, R.J. (2016). In Vitro Characterization of Chain Depolymerization Activities of SUMO-Specific Proteases. Methods Mol. Biol. 1475:123-35.
Faden, F., Ramezani, T., Mielke, S., Almud,i I., Nairz. K, Froehlich, M.S., Hockendorff. .J, Brandt, W., Hoehenwarte, W., Dohmen, R.J., Schnittger, A., and Dissmeyer, N. (2016). Phenotypes on demand via switchable target protein degradation in multicellular organism. Nature Commun. 2016 Jul 22;7:12202. doi: 10.1038/ncomms12202. full text
Dohmen, R.J. (2015). SUMO wrestles down MYC. Cell cycle. Volume 14, Issue 16, 2551-2552. full text
Kock, M., Nunes, M.M., Hemann, M., Kube, S., Dohmen, R.J., Herzog, F., Ramos, P.C., and Wendler P. (2015) Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperone. Nature Commun. 2015 Jan 22;6:6123. doi: 101038/ncomms7123 full text
Dohmen, R.J. (2015). Starting with a degron: N-terminal formyl-methionine of nascent bacterial proteins contributes to their proteolytic control. Microbial Cell 2, 356-359. full text
Beenukumar, R., Gödderz, D., Palanimurugan, R., and Dohmen, R.J., (2015). Polyamines directly promote antizyme-mediated degradation of ornithine decarboxylase by the proteasome. Microbial Cell 2, 197-205. full text
Eckhoff, J., and Dohmen, R.J. (2015). In vitro studies reveal a sequential mode of chain processing by the yeast SUMO-specific protease Ulp2.J. Biol. Chem. May 8; 290, 12268-12281. doi: 10.1074/jbc.M114.622217. Epub 2015 Apr 1. full text
Kock, M., Nunes, M.M., Hemann, M., Kube, S., Dohmen, R.J., Herzog, F., Ramos, P.C., and Wendler P. (2015) Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperone. Nature Commun. 2015 Jan 22;6:6123. doi: 101038/ncomms7123 full text
Palanimurugan, R., Kurian, L., Hegde, V., Hofmann, K., and Dohmen, R.J., (2014) Co-translational polyamine sensing by nascent polypeptide. In: Ito, K. Regulatory Nascent Polypeptide, Springer, DOI 10.1007/978-4-431-55052-5_12
Keusekotten, K., Bade, V.N., Meyer-Teschendorf, K., Sriramachandran, A.M., Fischer-Schrader, K., Krause, A., Hors, C., Schwarz, G.,Hofmann, K., Dohmen, R.J., andPraefck, G.J.K. (2014) Multivalent interactions of the SUMO-interaction motifs in the RING-finger protein 4 (RNF4) determine the specificity for chains of the small ubiquitin-related modifier (SUMO). Biochem. J. 457, 207-214. full text
Sa-Moura, B., Funakoshi, M., Tomko, R.J. Jr., Dohmen, R.J., Wu, Z., Peng, J., and Hochstrasser, M. (2013) A Conserved Protein with AN1 Zinc-finger and Ubiquitin-like Domains Modulates Cdc48 (p97) Function in the Ubiquitin-Proteasome Pathway. J. Biol. Chem .288, 33682-33696 full text
Sa-Moura, B., Marisa Simoes, A.M., Fraga, J., Fernandes, H., Abreu, I.A., Botelho, H.M., Gomes, C.M., Marques, A.M., Dohmen, R.J., Ramos, PC, Macedo-Ribeiro, S. (2013 ) Biochemical and Biophysical Characterization of Recombinant Yeast Proteasome Maturation Factor Ump1. Comput. Struct. Biotechnol. J. Volume No: 7, Issue: 8, April 2013, e201304006. full text
Sriramachandran, A.M., and Dohmen, R.J. (2013) SUMO-targeted ubiquitin ligases. Biochim. Biophys. Acta. 2013 Sep 7. doi:pii: S0167-4889(13)00321-2. 10.1016/j.bbamcr.2013.08.022. full text
Gowda, N.K., Kandasamy, G., Froehlich, M.S.., Dohmen, R.J., and Andreasson, C.. (2013) Hsp70 nucleotide exchange factor Fes1 is essential for ubiquitin-dependent degradation of misfolded cytosolic proteins. Proc. Natl. Acad. Sci. USA 110, 5975-5980. abstract
Schnellhardt, M., Uzunova, K., Bade, V.N., Krause, A., Weisshaar, S.R. Praefcke, G.J,K, and Dohmen, R.J. (2012) Analysis of cellular SUMO and SUMO-ubiquitin hybrid conjugates. Methods in Molecular Biology 832, 82-91. abstract
Praefcke, G.J,K, Hofmann, K., and Dohmen, R.J. (2012) SUMO playing tag with ubiquitin.Trends in Biochemical Sciences, 37, 23-11. abstract
Kurian, L., Palanimurugan, R., Gödderz, D., and Dohmen RJ. (2011). Polyamine sensing by nascent ornithine decarboxylase antizyme stimulates decoding of its mRNA. Nature 477, 490-494. abstract
Gödderz, D., Schäfer, E., Palanimurugan, R., Dohmen, R.J. (2011). The N-terminal unstructured domain of yeast ODC functions as a transplantable and replaceable ubiquitin-independent degron. J. Mol. Biol. 407, 354-367. abstract
Hermkes, R., Fu, Y.F., Nürrenberg, K., Budhiraja, R., Schmelzer, E., Elrouby, N., Dohmen, R.J., Bachmair, A., Coupland, G. (2011). Distinct roles for Arabidopsis SUMO protease ESD4 and ist closest homolog ELS1. Planta 233, 63-73. full text
Miteva, M., Keusekotten, K., Hofmann, K., Praefcke, G.J.K., and Dohmen, R.J. (2010). Sumoylation as a signal for polyubiquitylation and proteasomal degradation. Subcell. Biochem. 54, 195-214. free full text
Matias, A.C., Ramos, P.C., and Dohmen, R.J. (2010). Chaperone-assisted assembly of the proteasome core particle. Biochem. Soc. Trans. 38, 29-33. abstract
Marques, A.J., Palanimurugan, R., Matias, A.C., Ramos, P.C., and Dohmen, R.J. (2009). Catalytic mechanism and assembly of the proteasome. Chem. Rev. 109, 1509-1536. link Chem Rev.
Gödderz, D. and Dohmen, R.J. (2009). Hsm3/S5b joins the ranks of 26s proteasome assembly chaperones. Mol. Cell 16, 1296-1304. abstract
Ramos, P.C., Dohmen, R.J. (2008). PACemakers of proteasome core particle assembly. Structure 16, 1296-1304. abstract
Weisshaar, S.R., Keusekotten, K., Krause, A., Horst, C., Springer, H.M., Göttsche, K., Dohmen, R.J. and Praefcke, G.J. (2008). Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML. FEBS Lett. 582, 3174-3178. abstract
Marques, A.J., Glanemann, C., Ramos, P.C., and Dohmen, R.J. (2007). The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20S proteasomes and promote their maturation J. Biol. Chem. 282, 34869-34876. abstract (figure mentioned as data not shown, originally submitted as supplemental figure download)
Uzunova, K., Göttsche, K., Miteva, M., Weisshaar, S.R., Glanemann, Schnellhardt, M., Niessen, M., C., Scheel, H., Hoffmann, K., Johnson, E.S., Praefcke, G.J.K. and Dohmen, R.J. (2007). Ubiquitin-dependent Proteolytic control of SUMO conjugates. J. Biol. Chem. 282, 34167-34175. abstract
Dohmen, R.J., Willers, I., and Marques, A.J. (2007). Biting the hand that feeds: Rpn4-dependent feedback regulation of proteasome function. Biochim. Biophys. Acta. 1773, 1599-1604. full text
Chen, Q., Thorpe, J., Dohmen, R.J., Li, F. and Keller, J.N. (2006) Ump1 extends yeast lifespan and enhances viability during oxidative stress: Central role for the proteasome? Free Radic. Biol. Med. 40, 120-126. abstract
Dohmen, R.J. (2006) Inducible degron and its application to creating conditional mutants. Methods Mol. Biol. 313, 145-160. abstract
Dohmen, R.J. and Varshavsky, A. (2005) Heat-inducible degron and the making of conditional mutants. Methods Enzymol. 399, 799-822. abstract
Dohmen, R.J., London, M.K., Glanemann, C., and Ramos, P.C. (2005) Assays for proteasome assembly and maturation. Methods Mol. Biol. 301, 83-96. abstract
Dohmen, R.J. SUMO protein modification. (2004) Biochim. Biophys. Acta. 1695, 113-131. abstract
Palanimurugan, R., Scheel, H., Hofmann, K., and Dohmen, R.J. (2004) Polyamines regulate their synthesis by inducing expression and blocking degradation of ODC antizyme. EMBO J. 23, 4857-4867. full text
London, M.K., Keck, B.I:, Ramos, P.C. and Dohmen, R.J. (2004) Regulatory mechanisms controlling biogenesis of ubiquitin and the proteasome. FEBS Lett. 567, 259-264. abstract
Ramos, P.C., Marques, A.J., London, M.K., and Dohmen, R.J. (2004). Role of C-terminal extensions of subunits beta2 and beta7 in assembly and activity of eukaryotic proteasomes. J. Biol. Chem. 279, 14323-14330. abstract
Dohmen, R.J. (2003) Ubiquitin/proteasome system. In: S. Offermanns, and W. Rosenthal (eds.): Molecular pharmacology: an encyclopedic reference. Springer, Heidelberg, p. 943-948. full text
Dohmen, R.J. (2003). Ubiquitin-related modifiers. In: S. Offermanns and W. Rosenthal (eds.): Molecular pharmacology: an encyclopedic reference. Springer, Heidelberg, p. 948-951. full text
Stade, K., Vogel, F., Schwienhorst, I., Volkwein, C., Meusser, B., Dohmen, R.J. and Sommer, T. (2002). Mutants of the SUMO modification system affect a specific nuclear protein import pathway in yeast. J. Biol. Chem. 277, 49554-49561. full text
Dohmen, R.J. (2000). Primary Destruction signals. In W. Hilt, and D.H. Wolf (eds.): Proteasomes: the world of regulatory proteolysis. Eurekah.com/Landes Biosciences, Georgetown, Texas, USA, pp. 186-198.full text
Verma, R., Chen, S., Feldman, R., Schieltz, D., Yates, J., Dohmen, J., and Deshaies, R.J. (2000) Proteasomal proteomics: Identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol. Biol. Cell 11, 3425-3439. full text
Burri, L., Höckendorff, J., Boehm U., Klamp, T., Dohmen, R.J., and Lévy, F. (2000) Identification and characterization of a mammalian protein interacting with 20S proteasome precursors. Proc. Natl. Acad. Sci. USA 97, 10348-10353. full text
Schwienhorst, I., Johnson, E.S., and Dohmen, R.J. (2000). SUMO conjugation and deconjugation. Mol. Gen. Genet. 263, 771-786. full text
Varshavsky, A., Byrd C., Davydov. I.V., Dohmen, R.J., Du, F., Ghislain, M., Gonzalez, M., Grigoryev, S., Johnson, E.S., N. Johnson, N., Johnston, J.A., Kwon, Y.T., Lévy, F., Lomovskaya, O., Madura, K., Ota, I., Rümenapf, T., Shrader, T.E., Suzuki, T., Turner, G., Waller P.R.H., Webster, A. and Xie, Y. (1998) The N-end rule pathway. In Peters, J.-M., Harris, J.R. and Finley, D. (eds.) Ubiquitin and the biology of the cell. pp. 223-278, Plenum Publishing Company Ltd, London.
Ramos, P.C., Höckendorff, J., Johnson, E., Varshavsky, A., and Dohmen, R.J. (1998) Ump1p is required for maturation of the 20S proteasome, and becomes its substrate upon completion of the assembly. Cell 20, 489-499. abstract
Johnson, E.S., Schwienhorst, I., Dohmen, R. J., and Blobel G. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J. 16, 5509-5519. full text
Hülseweh, B., Dahlems, U.M., Dohmen, R.J., Strasser A.W.M., Hollenberg, C.P. (1997) Characterization of the active site of Schwanniomyces occidentalis glucoamylase by in vitro mutagenesis. Eur. J. Biochem. 244, 128-133. abstract
Ghislain, M., Dohmen, R.J., Lévy, F., and Varshavsky, A. (1996) Cdc48p interacts with Ufd3p, a WD-repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. EMBO J.. 15, 4884-4899. abstract
Dohmen, R.J., and Hollenberg, C.P. (1996) Schwanniomyces occidentalis. In K. Wolf (ed): Non-conventional yeasts in Biotechnology. Scientific Publishing Services, Springer, Germany, p. 117-137.
Dohmen, R.J., Stappen, R., McGrath J.P., Forrová, H., Kolarov, J., Goffeau,A., and Varshavsky, A. (1995). An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. J. Biol Chem. 270, 18099-18109. full text
Dohmen, R.J., Wu, P., and Varshavsky, A. (1994) Heat-inducible degron: a method for constructing temperature-sensitive mutants. Science 263, 1273-1276. abstract
Madura, K., Dohmen, R.J., and Varshavsky, A. (1993) N-recognin/Ubc2 interactions in the N-end rule pathway. J. Biol. Chem. 268, 12046-12054. abstract
Dohmen, R.J., Madura, K., Bartel, B. and Varshavsky, A. (1991) The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme. Proc. Natl. Acad. Sci. USA 88, 7351-7355. full text
Strasser, A.W.M., Janowicz, Z.A., Roggenkamp, R.O., Dahlems, U., Weydemann, U., Merckelbach, A., Gellissen, G., Dohmen, R.J., Piontek, M., Melber, K. and Hollenberg, C.P. (1991) Applications of genetically manipulated yeasts. In Peberdy, J.F., Caten, C.E., Ogden, J.E. and Bennett, J.W. (eds.) Applied molecular genetics of fungi, Cambridge University Press, 161-169.
Dohmen, R.J., Strasser, A.W.M., Höner, C.B. and Hollenberg, C.P. (1991) An efficient transformation procedure enabling long-term storage of competent cells of various yeast genera. Yeast 7, 691-692.
Dohmen, R.J., Strasser, A.W.M., Dahlems, U.M. and Hollenberg, C.P. (1990) Cloning of the Schwanniomyces occidentalis glucoamylase gene (GAM1) and its expression in Saccharomyces cerevisiae. Gene 95, 111-121. abstract
Strasser, A.W.M. , Selk,R. Dohmen,R.J.,Niermann,T., Bielefeld,B., Seeboth,P., Guihong,T. and Hollenberg, C.P. (1989) Analysis of the a-amylase gene of Schwanniomyces occidentalis and the secretion of its gene product in transformants of different yeast genera. Eur. J. Biochem. 184, 699-706. abstract
Dohmen, R.J., Strasser, A.W.M., Zitomer, R.S. and Hollenberg, C.P. (1989) Regulated overproduction of a-amylase by transformation of the amylolytic yeast Schwanniomyces occidentalis. Curr. Genet. 15, 319-325. abstract