Gene expression is the fundamental process that uses the genomic information in order to synthesize gene products. We focus on understanding the general mechanisms and processes that regulate gene expression and thereby ensure faithful protein production. Specifically, we are interested how ribonucleoprotein (RNP) complexes influence various stages of the messenger RNA (mRNA) lifecycle. More detailed information about ongoing research projects in the lab can be found below.
Happy Birthday Sabrina!
Flower Power is strong with the Gehring Lab
Kölle Alaaf 2023
Great costumes and Kölsch make Carnival perfect
Lab christmas event 2021
Fun and sore muscles from LaserTag
Now published in Nature Communications!
Check out the final version of our "two-factor authentication" NMD story - with new evidence supporting the role of SMG5-SMG7 in NMD (click picture for direct link)
Congratulations Lisa!
Great B.Sc. thesis - one step closer to figuring out how the EJC regulates alternative splicing
Great collaboration with the Uhlirova lab on splicing regulation in Drosophila
Read more about how Ecd promotes U5 snRNP maturation and Prp8 stability in this work by Steffen Erkelenz and colleagues (click picture for direct link)
CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex
Now published in Nucleic Acids Research (click picture for direct link)!
A Day in the Life of the Exon Junction Complex
Review from Lena and Niels on a regular "day" in the life of the EJC (click picture for direct link)
CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex
First preprint from the Gehring lab, many thanks to all co-authors!
Oktoberfest 2019
O'Zapft is! Celebrating Bavarian beer culture
Protein Synthesis and Translational Control
Presented our latest story in the mRNA turnover session. Delighted about the return of the EMBO photo booth.
RNA 2019 conference in beautiful Kraków
Exciting talks in a great venue and city, plus another reunion of Gehringians!
Dominik Aschemeier
Lisa Bank
Simona Ciriello
Tobias Fatscher
Jennifer Gerbracht
Agnieszka Gromadzka
Julia Keloglou
Marie Charlotte Marx
Barbara Maubach
Svenja Meyer
Franziska Ottens
Karina Polkovnychenko
Franz Reichel
Lena Schlautmann
Kusum Singh
Anna-Lena Steckelberg
Joanna Swierz
Heidi Thelen
Benjamin Weiche
Please send inquiries for Bachelor and Master theses or laboratory modules including a short CV to Niels Gehring