Seminars and meetings
|Seminars of the Institute for Genetics|
Statistics / Statistical evaluation of data
|McDonald, J.H. 2014. Handbook of Biological Statistics, 3rd ed. Sparky House Publishing, Baltimore, Maryland.|
|... and as pdf (2nd edition)|
Maps: e.g. Mouse brain
(don't forget to download and install the Brain Explorer before first use....!)
E. Lein, M. Hawrylycz, et. al.: Genome-wide atlas of gene expression in the adult mouse brain..
Nature 445, pp. 168 - 176 (2007).
Yeast databases / AAA server
|DRYGIN: Data Repository of Yeast Genetic Interactions
DRYGIN is a database of quantitative genetic interactions of S. cerevisiae derived from the SGA double-mutant arrays
conducted in Boone lab at Terrence Donnelly Centre for Cellular and Biochemical Research, University of Toronto.
Judice L.Y. Koh et al. Nucleic Acids Research, 2010, Vol. 38, Database issue D502-D507:
"DRYGIN: a database of quantitative genetic interaction networks in yeast"
|Protein complexes in yeast
Gavin et al.: Proteome survey reveals modularity of the yeast cell machinery. Nature (2006).
|SCPD - The Promoter Database of Saccharomyces cerevisiae|
|CYGD / Comprehensive Yeast Genome Database|
|Incyte: YPD Database.|
|Saccharomyces Genome Database|
|Welcome to MIPS / MIPS homepage|
|MEROPS - The Protease Database|
|Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes
Web supplement to Gasch et al. (2000) Mol.Biol.Cell 11(12), 4241-4257
|MitoP2 - Mitochondrial Proteome Database for yeast and human|
|Human gene database, with Integrative Annotation Validated by Full-Length cDNA Clones|
|Predictions of C. elegans Genetic Interactions
W. Zhong and P.W. Sternberg: Genome-Wide Prediction of C. elegans Genetic Interactions.
Science 311, pp. 1481 - 1484 (2006).
Protein analysis: sequences & structures:
Domain searches, BLAST, Prediction of Transmembrane domains etc.
|HEFalMp||HEFalMp: a functional map of the human genome.
Functional maps offer a way to interactively explore gene, pathway, process, and disease associations predicted from integrating hundreds of publicly available genomic datasets.
Curtis Huttenhower et al.. Exploring the human genome with functional maps, Genome Research 2009, PMID 19246570
|Prediction of subcellular localisation of proteins||
TargetP 1.1 predicts the subcellular location of eukaryotic proteins. The location assignment is based on the predicted presence of any of the N-terminal presequences: chloroplast transit peptide (cTP), mitochondrial targeting peptide (mTP) or secretory pathway signal peptide (SP).
A prediction service for identifying putative N-terminal targeting sequences
Prediction of mitochondrial targeting sequences
Protein Subcellular Localization Prediction
Prediction of protein localization sites in cells
A genome-scale method for predicting mitochondrial proteins
restricted access: local / Cologne
|EBI||European Bioinformatics Institute|
|NCBI||National Center for Biotechnology Information|
|DDBJ||DDBJ (DNA Data Bank of Japan)|
Protein Data Bank Archive of macromolecular structural data
including direct submission to other prediction servers: Source of servers
The ExPASy (Expert Protein Analysis System) proteomics server of the Swiss Institute of Bioinformatics (SIB) is dedicated to the analysis of protein sequences and structures as well as 2-D PAGE
Direct access to the Prosite server at ExPASy
|Servers dedicated to the prediction of transmembrane regions|
|REBASE: restriction enzymes, methylases, isoschizomers....||The Restriction Enzyme Database|
|The Protein Domain Database - ProDom||ProDom is a comprehensive set of protein domain families automatically generated from the SWISS-PROT and TrEMBL sequence databases|
|The NCBI BLAST homepage||The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences.....|
Literature / Papers.....
|PubMed at the NCBI|
|ZBMed Cologne: online full-text access to many journals|
|Universitäts- und Stadtbücherei: online full-text access to many journals|
|Cluster of Excellence: Cellular Stress Responses in Aging-Associated Diseases (CECAD)|
|Zentrum für Molekulare Medizin Köln - ZMMK|
|Sonderforschungsbereich 635: Posttranslational control of protein function|
|International Graduate School in Genetics and Functional Genomics|
last modification: Oct. 05, 2016