Institute of Genetics - University of Cologne
Section of Molecular Genetics
Transcription factors:
Protein-DNA and Protein-Protein Interactions
Section Head: Benno Müller-Hill
Publications 1998-2001
Publications in Molecular Genetics
Publications in Biochemistry and Genetics in Journals
1) Minn, A., Schubert, M., Neiss, W.F. & Müller-Hill, B.: Enhanced GFAP expression in
astrocytes of transgenic mice expressing the human brain-specific trypsinogen IV. Glia 22, 338-347
(1998).
2) Barker, A., Fickert, R., Oehler, S. & Müller-Hill, B.: Operator search by mutant Lac
repressors. J.Mol.Biol. 278, 549-558 (1998).
3) Schlieper, D., Wilcken-Bergmann, B.v., Schmidt, M., Sobek, H. & Müller-Hill, B.: A positive
selection vector for cloning of long PCR fragments based on a lethal mutant of the crp gene of
Escherichia coli. Anal.Biochem. 257, 203-209 (1998).
4) Müller-Hill, B.: Some repressors of bacterial transcription. Current Opinion in Microbiology 1,
145-151 (1998).
5) Müller-Hill, B.: The function of auxiliary operators. Mol.Microbiol. 29, 13-18 (1998).
6) Barker, A. & Müller-Hill, B.: Towards a mutant analysis of the tertiary structures of functional
DNA-binding motifs. FEBS Letters 432, 1-3 (1998).
7) Müller, J., Barker, A., Oehler, S. & Müller-Hill, B.: Dimeric Lac repressors exhibit phase-
dependent co-operativity. J. Mol.Biol. 284, 851-857 (1998).
8) Révet, B., Wilcken-Bergmann, B.v., Bessert, H., Barker, A. & Müller-Hill, B.: Four dimers of
λ repressor bound to two suitably spaced pairs of λ operators form octamers and DNA loops over
large distances. Current Biology 9, 151-154 (1999).
9) Dong, F., Spott, S., Zimmermann, O., Kisters-Woike, B., Müller-Hill, B. & Barker, A.:
Dimerisation mutants of Lac repressor I: a monomeric mutant L251A that binds lac operator DNA as
a dimer. J.Mol.Biol. 290, 653-666 (1999).
10) Spott, S., Dong, F., Kisters-Woike, B. & Müller-Hill, B.: Dimerisation mutants of Lac
repressor. II: a single amino acid substitution, D278L, changes the specificity of dimerisation.
J.Mol.Biol. 296 (2), 673-684 (2000).
11) Pereg-Gerk, L., Leven, O. & Müller-Hill, B.: Increasing the thermostability of Lac repressor by
40°C. J.Mol.Biol. 299, 805-812 (2000).
12) Kisters-Woike, B., Vangierdegom, C. & Müller-Hill, B.: On the conservation of protein
sequences in evolution. TiBS 9, 419-421 (2000). Macromolecular interactions tracing the roots. TIBS 26,91 (2001).
13) Dröge, P. & Müller-Hill, B.: High local protein concentrations at promoters: strategies in
prokaryotic and eukaryotic cells. Bioessays 23, 1-6 (2000).
14) Pereg-Gerk, L. & Müller-Hill, B.: Oligomerisation, a factor in thermostability of Lac repressor.
Mol. Microbiol., submitted.
Publications in Biochemistry and Genetics in Books
Müller-Hill, B.: Isopropyl-1-thio-β-D-galactopyranoside/lac operon/Lac repressor. In:
Encyclopedia of Molecular Biology, Wiley, New York, 1324-25; 1355-1356; 1357-1358 (1999).
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Genetics
Publications in History, Sociology and Philosophy of Science
Publications in Journals and Books
1) With Ute Deichmann: The fraud of Abderhalden's enzymes. Nature 393, 109-111 (1998).
2) Book Review: Henry Friedlander: Der Weg zum NS-Genozid. Von der Euthanasie zur
Endlösung. Berlin-Verlag 1997. Frankfurter Allgemeine Zeitung Nr. 39, p.9, 12. Feb. 1998.
3) Warum wurden wir Mitglieder des SDS 1946-1960? 1999 - Zeitschrift für Sozialgeschichte des
20. Und 21. Jahrhunderts 13, Heft 2, 172-189 (1998).
4) Book Review: Eugenics and the Welfare State. N. Roll-Hansen & G. Broberg, Eds. Michigan
State University Press 1996, and L. Koch: Racehygiejne i Danmark, Gyldendal 1996. 1999
Zeitschrift für Sozialgeschichte des 20. u. 21. Jahrhunderts, Heft 2, 217-219 (1998).
5) The different faces of science: is genetics a social construct? From Physico-Theology to
Biotechnology. A Festschrift for Mikulas Teich. Ed. by K. Bayertz and R. Porter. Rodopi,
Amsterdam-Atlanta, 40-53 (1998).
6) Auslaufmodel Humboldt. Laborjournal, Heft 8, 5 (1998).
7) With Frank Schneider and Peter Dröge: Links ist bisweilen, aber nicht immer richtig.
Laborjournal, Heft 9, 42 (1998).
8) Book Review: I wish I'd made you angry earlier. Max Perutz. Cold Spring Harbor Laboratory
Press, 1999. TIBS 24, 124-125 (1999).
9) With Frank Schneider and Peter Dröge: Sinister depiction of DNA. Trends in Genetics 15, 95
(1999).
10) In der Pedosphäre. Laborjournal Heft 7, 5 (1999).
11) Book Review: Die Deutsche Forschungsgemeinschaft in der Weimarer Republik und im Dritten
Reich, Notker Hammerstein. C.H.Beck Verlag, München. Laborjournal Heft 8, 50 (1999).
12) Towards a linguistics of DNA and protein. History and Philosophy of Life Sciences 21, 53-63
(1999).
13) Book review: Proteins, Enzymes, Genes. The Interplay of Chemistry and Biology, Joseph S.
Fruton. Yale University Press. Angewandte Chemie Int. Ed. 38, pp. (1999).
14) Book review: Sverige och Förintelsen. I. Svanberg and M. Tyden, Arena, Stockholm 1997. 1999
Zeitschrift für Sozialgeschichte des 20. u. 21. Jahrhunderts Heft 2/99, 208-209 (1999).
15) Die Befreiung der Doktoranden. Laborjournal Heft 10, 11 (1999).
16) Book review: Elementarteilchen. M. Houllebecq, Dumont. Laborjournal Heft 1, 66-67 (2000).
17) Murderous Science - Murderous Silence: a Conversation with Benno Müller-Hill. Chemical
Intelligencer 8 (no.1), 18-24, 2000.
18) Warum spricht der Mensch? Laborjournal Heft 4, 14 (2000).
19) Oscar's gurken, Laborjournal Heft 5, 6 (2000).
20) Die Diskriminierung der Alten. Amerika Du hast es besser. Laborjournal Heft 7, 7 (2000).
21) Der Abtrünnige. Fackel im Herzen: Der Biochemiker Erwin Chargaff wird 95. Frankfurter
Allgemeine, 11.08.2000.
22) Book review: A history of molecular biology, by M. Morange. Harvard University Press.
EMBO Reports 1, 106 (2000).
23) Truth, Justice and Genetics. In: Perspectives in Biology and Medicine, Perspectives in Biology
& Medicine 43, 577-583 (2000).
24a) Das Blut von Auschwitz und das Schweigen der Gelehrten. In: Geschichte der KWG im
Nationalsozialismus, ed. by D. Kaufmann. Wallstein-Verlag, Göttingen, 189-227 (2000).
24b)English version: The Blood from Auschwitz and the Silence of the Scholars. History and
Philosophy of Life Sciences 21, 331-365 (1999).
25) Warum schweigen die deutschen Gen-Forscher? James Watson ist doch einer der Größten in
unserem Feld, Ein Schüler verteidigt seinen Lehrer. Frankfurter Allgemeine Zeitung, 28.11.2000.
26) The implications of modern genetics and the consequences of genetic knowledge for our world
view. In: International Seminar on Nuclear War and Planetary Emergencies. 24th session. Ed. by A.
Zichichi and R. Ragaini, World Scientific Publishing, 121-126 (2000).
27) Reflections on the Use of Interviews in the History of Science: Who Will Write the History of
Science? His.Phil.Life Sci. 23, 107-118 (2001).
28) Book review: The Nazi persecution of the Gypsies, by Guenter Lewi. Oxford University Press,
Oxford. His.Phil.Life Sci. 22, 208-210 (2001).
29) Book review: Inventing the criminal, a history of German criminology 1880-1945, by Richard
F. Wetzel. The University of North Carolina Press, Chapel Hill/London. His.Phil.Life Sci. 22, 220-
221 (2001).
30) Genetics of susceptibility to tuberculosis: Mengele's experiments in Auschwitz. Nature Rev.
Genetics 2,631-634 (2001).
31) Die Gefahr der Eugenik. In: Was wissen wir, wenn wir das menschliche Genom kennen? 220-221 (2001).
32) Erinnerung ist Voraussetzung aller Ethik: Der Fall der deutschen Humangenetik. In: Ethische
Probleme in den Biowissenschaften. M. Weber & P. Hoyningen-Huene (eds.). Karl Alber-Verlag,
Freiburg, 171-189 (2001).
Books
The lac operon: a short history of a genetic paradigm. Walter deGruyter, Berlin (1996). Japanese
translation. Springer, Tokio (1998).
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