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Batch 2001
The first batch of 13 international students accepted for the International Graduate School in Genetics and Functional Genomics came from Taiwan, Turkey, China, Bulgaria, India and Germany.
Cemalettin Bekpen
Date of birth: 07.07.1974
Nationality: Turkish
Email:bekpen@u.washington.edu
Webpage: http://eichlerlab.gs.washington.edu/cemal.html
Current occupation, interests
July 2006 - present
Postdoctoral Fellow at Eichler Lab, Department of Genome Sciences, University of Washington, USA
I am interested in studying function of segmentally duplicated genes and/or gene families. Segmental duplication play an important role in evolution as they are plastic regions of rapid structural change, chromosomal instability and rearrangement. Moreover, gene duplications are considered to be a mechanism to increase the diversity of the gene families.
Understanding the function of the duplicated gene and/or families are crucial because survival and therefore selection of a species depends on the ability to fight with infectious agants and environmental changes.
Currently, I am analyzing the function of Morpheus and LRRC37 gene family that are segmentally duplicated.
PhD
Supervisor/ Institute
Prof. Dr. Jonathan C. Howard/ Institute of Genetics
Title of the thesis:
Evolutionary and functional studies of p47 GTPases involved in cell autonomous immunity
Thesis committee
Prof. Dr Jonathan Howard and Prof Dr. Diethard Tautz
Date of defense
14. February 2006
Field of studies
The p47 GTPases gene family is documented down to the mouse, human, dog, rat and bony fishes. The dramatic gain and loss of the family member is shown in these ancient taxonomic groups. The clear distinction between mouse and human immune system in regards to cell autonomous immunity is discovered.
University
Supervisor:Prof. Dr. Inci Togan
Population Genetics
M. Sc. thesis: "DNA isolation and PCR amplification from sheep samples obtained by non-destructive sampling"
Conferences and workshops
International Symposium on Health informatics and Bioinformatics (Apr. 2009) Invited Speaker. Title: "Comparative genomics analysis and dynamic structure of segmentally duplicated gene families"
Selected papers
- Bekpen C, Marques-Bonet T, Alkan C, Antonacci F, Leogrande MB, Ventura M, Kidd JM, Siswara P, Howard JC, Eichler EE. Death and resurrection of the human IRGM gene. PLoS Genet. 2009 Mar;5(3):e1000403. Epub 2009 Mar 6.
- Bekpen C, Hunn JP, Rohde C, Parvanova I, Guethlein L, Dunn DM, Glowalla E, Leptin M, Howard JC The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage. Genome Biol. 2005;6(11):R92. Epub 2005 Oct 31.
- Leonhardt RM, Keusekotten K, Bekpen C, Knittler MR. Critical role for the tapasin-docking site of TAP2 in the functional integrity of the MHC class I-peptide-loading complex. J Immunol. 2005 Oct 15;175(8):5104-14.
Comments about...
...IGS GFG:"I missed a lot of friends from Cologne. Those were the good times. I hope one day there will be a chance to meet with them."
... life philosophy :) "Let's drink for IRGM Dead or Alive !!!"
"Imagination is more important than knowledge (A. Einstein)"
...things I like to do in free time: "Playing games, football, violin, riding bicycle, driving the mustang. One day, I want to open my restaurant in Istanbul."
Christoph Glanemann
Nationality: German
Current occupation, interests
June 2009 - present
Project Manager: Trenzyme GmbH, Konstanz, Germany
2006 - 2009
Postdoctoral Research Fellow: Harvard Medical School, Boston, USA
PhD
Supervisor/ Institute
Prof. Dr. Jürgen Dohmen/ Institute of Genetics
Date of defense
2006
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