Publications

last update September 02, 2011

Fischer D, Clemen CS, Olive M, Ferrer I, Goudeau B, Roth U, Badorf P, Wattjes MP, Lutterbey G, Kral T, van der Ven PF, Fürst DO, Vicart P, Goldfarb LG, Moza M, Carpen O, Reichelt J, Schröder R,
Different early pathogenesis in myotilinopathy compared to primary desminopathy
Neuromuscul. Disord. 16, 361-7 (2006)

Goffart S, Franko A, Clemen CS, Wiesner RJ,
alpha-actinin 4 interaction with the Cytochrome c promoter upon skeletal muscle differentiation
Curr Genet 49, 125-35 (2006)

Arasada R, Son H, Ramalingam N, Eichinger L, Schleicher M, and Rohlfs M,
Characterization of the Ste20-like kinase Krs1 of Dictyostelium discoideum
Eur. J. Cell Biol. 85, 1059-1068 (2006)

Farbrother P, C. Wagner C, J. Na J, Tunggal B, Morio T, Urushihara H, Tanaka Y, Schleicher M, Steinert M, and Eichinger L,
Dictyostelium transcriptional host cell response upon infection with Legionella
Cell. Microbiol. 8, 438-456 (2006)

Yusof AM, Jaenicke E, Pedersen JS, Noegel AA, Schleicher M, Hofmann A.
Mechanism of oligomerisation of cyclase-associated protein from Dictyostelium discoideum in solution.
J Mol Biol. 362, 1072-81 (2006)


Rybakin V, Gounko NV, Spate K, Honing S, Majoul IV, Duden R, Noegel AA
Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi.
J Biol Chem. 281, 31070-78 (2006)


Bakthavatsalam D, Meijer HJ, Noegel AA, Govers F.
Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and Phytophthora.
Trends Microbiol. 14, 378-82 (2006)


Popowicz GM, Schleicher M, Noegel AA, Holak TA.
Filamins: promiscuous organizers of the cytoskeleton.
Trends Biochem Sci. 31, 411-9 (2006)


Marko M, Prabhu Y, Muller R, Blau-Wasser R, Schleicher M, Noegel AA.
The annexins of Dictyostelium.
Eur J Cell Biol. 85, 1011-22 (2006)


Chu H, Thievessen I, Sixt M, Lammermann T, Waisman A, Braun A, Noegel AA, Fassler R.
gamma-Parvin is dispensable for hematopoiesis, leukocyte trafficking, and T-cell-dependent antibody response.
Mol Cell Biol. 26, 1817-25 (2006)


Peracino B, Wagner C, Balest A, Balbo A, Pergolizzi B, Noegel AA, Steinert M, Bozzaro S.
Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection.
Traffic. 7, 22-38 (2006)


Kuhlmann M, Borisova BE, Kaller M, Larsson P, Stach D, Na J, Eichinger L, Lyko F, Ambros V, Söderbom F, Hammann Ch, and Nellen W,
Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi
Nucleic Acids Res. 33, 6405-6417 (2005)

Rosslenbroich V, Dai L, Baader SL, Noegel AA, Gieselmann V, Kappler J.
Collapsin response mediator protein-4 regulates F-actin bundling.
Exp Cell Res. 310, 434-44 (2005)


Sultana H, Rivero F, Blau-Wasser R, Schwager S, Balbo A, Bozzaro S, Schleicher M, Noegel AA.
Cyclase-Associated Protein is Essential for the Functioning of the Endo-Lysosomal System and Provides a Link to the Actin Cytoskeleton
Traffic. 6, 930-46 (2005)


Eichinger L, Noegel AA.
Comparative genomics of Dictyostelium discoideum and Entamoeba histolytica
Curr Opin Microbiol. 8, 606-11 (2005)


Wilkins A, Szafranski K, Fraser DJ, Bakthavatsalam D, Muller R, Fisher PR, Glockner G, Eichinger L, Noegel AA, Insall RH.
The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles
Genome Biol. 6, R68 (2005)


Padmakumar VC, Libotte T, Lu W, Zaim H, Abraham S, Noegel AA, Gotzmann J, Foisner R, Karakesisoglou I.
The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope
J Cell Sci. 2005 Aug 1;118(Pt 15):3419-30


Clemen CS, Fischer D, Roth U, Simon S, Vicart P, Kato K, Kaminska AM, Vorgerd M, Goldfarb LG, Eymard B, Romero NB, Goudeau B, Eggermann T, Zerres K, Noegel AA, Schroder R.
Hsp27-2D-gel electrophoresis is a diagnostic tool to differentiate primary desminopathies from myofibrillar myopathies.
FEBS Lett. 579, 3777-82 (2005).


Williams JG, Noegel AA, Eichinger L.
Manifestations of multicellularity: Dictyostelium reports in.
Trends Genet. 21, 392-8 (2005)


Eichinger L, Pachebat JA, Glockner G, Rajandream MA, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov BA, Rivero F, Bankier AT, Lehmann R, Hamlin N, Davies R, Gaudet P, Fey P, Pilcher K, Chen G, Saunders D, Sodergren E, Davis P, Kerhornou A, Nie X, Hall N, Anjard C, Hemphill L, Bason N, Farbrother P, Desany B, Just E, Morio T, Rost R, Churcher C, Cooper J, Haydock S, van Driessche N, Cronin A, Goodhead I, Muzny D, Mourier T, Pain A, Lu M, Harper D, Lindsay R, Hauser H, James K, Quiles M, Madan Babu M, Saito T, Buchrieser C, Wardroper A, Felder M, Thangavelu M, Johnson D, Knights A, Loulseged H, Mungall K, Oliver K, Price C, Quail MA, Urushihara H, Hernandez J, Rabbinowitsch E, Steffen D, Sanders M, Ma J, Kohara Y, Sharp S, Simmonds M, Spiegler S, Tivey A, Sugano S, White B, Walker D, Woodward J, Winckler T, Tanaka Y, Shaulsky G, Schleicher M, Weinstock G, Rosenthal A, Cox EC, Chisholm RL, Gibbs R, Loomis WF, Platzer M, Kay RR, Williams J, Dear PH, Noegel AA, Barrell B, Kuspa A.
The genome of the social amoeba Dictyostelium discoideum.
Nature. 435, 43-57 (2005).


Libotte T, Zaim H, Abraham S, Padmakumar VC, Schneider M, Lu W, Munck M, Hutchison C, Wehnert M, Fahrenkrog B, Sauder U, Aebi U, Noegel AA, Karakesisoglou I.
Lamin A/C Dependent Localization of Nesprin-2, a Giant Scaffolder at the Nuclear Envelope.
Mol Biol Cell. 16, 3411-24 (2005)


Rick M, Ramos Garrido SI, Herr C, Thal DR, Noegel AA, Clemen CS.
Nuclear localization of Annexin A7 during murine brain development.
BMC Neurosci. 6, 25 (2005)

Hasse A, Rosentreter A, Spoerl Z, Stumpf M, Noegel AA, Clemen CS.
Coronin 3 and its role in murine brain morphogenesis. Eur J Neurosci. 21, 1155-68 (2005)

Felder M, Szafranski K, Lehmann R, Eichinger L, Noegel AA, Platzer M, Glockner G.
DictyMOLD-a Dictyostelium discoideum genome browser database.
Bioinformatics. 21, 696-7 (2005)

Schwaiger I, Schleicher M, Noegel AA, Rief M.
The folding pathway of a fast-folding immunoglobulin domain revealed by single-molecule mechanical experiments.
EMBO Rep. 6, 46-51 (2005)

Knuth M, Khaire N, Kuspa A, Lu SJ, Schleicher M, Noegel AA.
A novel partner for Dictyostelium filamin is an {alpha}-helical developmentally regulated protein.
J Cell Sci. 117, 5013-5022 (2004)


Popowicz GM, Muller R, Noegel AA, Schleicher M, Huber R, Holak TA.
Molecular structure of the rod domain of dictyostelium filamin.
J Mol Biol. 342, 1637-46 (2004)


Rybakin V, Stumpf M, Schulze A, Majoul IV, Noegel AA, Hasse A.
Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.
FEBS Lett. 573, 161-7 (2004)


Padmakumar VC, Abraham S, Braune S, Noegel AA, Tunggal B, Karakesisoglou I, Korenbaum E.
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton.
Exp Cell Res. 295, 330-9 (2004)


Mavoungou C, Israel L, Rehm T, Ksiazek D, Krajewski M, Popowicz G, Noegel AA, Schleicher M, Holak TA.
NMR structural characterization of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum.
J Biomol NMR. 29, 73-84 (2004)


Schwaiger I, Kardinal A, Schleicher M, Noegel AA, Rief M.
A mechanical unfolding intermediate in an actin-crosslinking protein.
Nat Struct Mol Biol. 11, 81-5 (2004).


Noegel AA, Blau-Wasser R, Sultana H, Muller R, Israel L, Schleicher M, Patel H, Weijer CJ.
The Cyclase-associated Protein CAP as Regulator of Cell Polarity and cAMP Signaling in Dictyostelium.
Mol Biol Cell. 15, 934-45 (2004)


Fajardo M, Schleicher M, Noegel A, Bozzaro S, Killinger S, Heuner K, Hacker J, Steinert M.
Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum
Microbiology. 150, 2825-35 (2004)

Van Impe K, De Corte V, Eichinger L, Bruyneel E, Mareel M, Vandekerckhove J, and Gettemans J,
The nucleo-cytoplasmic actin binding protein CapG lacks a nuclear export sequence present in structurally related proteins
J. Biol. Chem. 278, 17945-17952 (2003)

Schröder R, Reimann J, Salmikangas P, Clemen CS, Hayashi YK, Nonaka I, Arahata K, Carpen O.
Beyond LGMD1A: myotilin is a component of central core lesions and nemaline rods
Neuromuscul. Disord. 13, 451-5 (2003)

Schröder R, Goudeau B, Simon MC, Fischer D, Eggermann T, Clemen CS, Li Z, Reimann J, Xue Z, Rudnik-Schöneborn S, Zerres K, van der Ven PF, Fürst DO, Kunz WS, Vicart P.
On noxious desmin: functional effects of a novel heterozygous desmin insertion mutation on the extrasarcomeric desmin cytoskeleton and mitochondria
Hum. Mol. Genet. 12, 657-69 (2003)

Clemen CS, Herr C, Hovelmeyer N, Noegel AA.
The lack of annexin A7 affects functions of primary astrocytes.
Exp Cell Res. 291, 406-14 (2003).


Ksiazek D, Brandstetter H, Israel L, Bourenkov GP, Katchalova G, Janssen KP, Bartunik HD, Noegel AA, Schleicher M, Holak TA.
Structure of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum
Structure (Camb). 11, 1171-8 (2003).


Herr C, Clemen CS, Lehnert G, Kutschkow R, Picker SM, Gathof BS, Zamparelli C, Schleicher M, Noegel AA.
Function, expression and localization of annexin A7 in platelets and red blood cells: Insights derived from an annexin A7 mutant mouse.
BMC Biochem. 4, 8 (2003).


Gloss A, Rivero F, Khaire N, Muller R, Loomis WF, Schleicher M, Noegel AA.
Villidin, a novel WD-repeat and villin-related protein from Dictyostelium, is associated with membranes and the cytoskeleton.
Mol Biol Cell. 14, 2716-27 (2003).


Eichinger L, Noegel AA.
Crawling into a new era-the Dictyostelium genome project.
EMBO J. 22, 1941-6 (2003).



Clemen CS, Herr C, Hovelmeyer N, Noegel AA.
The lack of annexin A7 affects functions of primary astrocytes.
Exp Cell Res. 291, 406-14 (2003).


Ksiazek D, Brandstetter H, Israel L, Bourenkov GP, Katchalova G, Janssen KP, Bartunik HD, Noegel AA, Schleicher M, Holak TA.
Structure of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum.
Structure (Camb). 11, 1171-8 (2003).


Schreiner T, Mohrs MR, Blau-Wasser R, von Krempelhuber A, Steinert M, Schleicher M, Noegel AA.
Loss of the F-actin binding and vesicle-associated protein comitin leads to a phagocytosis defect.
Eukaryot Cell. 6, 906-14 (2002).


Pergolizzi B, Peracino B, Silverman J, Ceccarelli A, Noegel A, Devreotes P, Bozzaro S.
Temperature-sensitive inhibition of development in Dictyostelium due to a point mutation in the piaA gene.
Dev Biol. 1, 18-26 (2002).


Farbrother P, Muller S, Noegel AA, Eichinger L.
Comparison of probe preparation methods for DNA microarrays.
Biotechniques. 33, 884, 886, 888 (2002).


Spoerl Z, Stumpf M, Noegel AA, Hasse A.
Oligomerization, F-actin interaction, and membrane association of the ubiquitous mammalian coronin 3 are mediated by its carboxyl terminus.
J Biol Chem. 277, 48858-67 (2002).


Khurana B, Khurana T, Khaire N, Noegel AA.
Functions of LIM proteins in cell polarity and chemotactic motility.
EMBO J. 21, 5331-42 (2002).


Hofmann A, Hess S, Noegel AA, Schleicher M, Wlodawer A.
Crystallization of cyclase-associated protein from Dictyostelium discoideum.
Acta Crystallogr D Biol Crystallogr. 58, 1858-61 (2002).


Zhen YY, Libotte T, Munck M, Noegel AA, Korenbaum E.
NUANCE, a giant protein connecting the nucleus and actin cytoskeleton.
J Cell Sci 115, 3207-22 (2002)


Glockner G, Eichinger L, Szafranski K, Pachebat JA, Bankier AT, Dear PH, Lehmann R, Baumgart C, Parra G, Abril JF, Guigo R, Kumpf K, Tunggal B, Cox E, Quail MA, Platzer M, Rosenthal A, Noegel AA, Barrell BG, Rajandream MA, Williams JG, Kay RR, Kuspa A, Gibbs R, Sucgang R, Muzny D, Desany B, Zeng K, Zhu B, De Jong P, Dingermann T, Gerisch G, Philippsen P, Schleicher M, Schuster SC, Winckler T.
Sequence and analysis of chromosome 2 of Dictyostelium discoideum.
Nature 418, 79-85 (2002).


Vardar D, Chishti AH, Frank BS, Luna EJ, Noegel AA, Oh SW, Schleicher M, McKnight CJ.
Villin-type headpiece domains show a wide range of F-actin-binding affinities.
Cell Motil Cytoskeleton 52, 9-21 (2002).


Khurana T, Khurana B, Noegel AA.
LIM proteins: association with the actin cytoskeleton.
Protoplasma 219, 1-12 (2002).


Janssen, K-P., R. Rost, L. Eichinger, and M. Schleicher.
Characterisation of CD36/LIMPII-Homologues in Dictyostelium discoideum.
J. Biol. Chem. 276, 38899-38910 (2001)

Korenbaum E, Olski TM, Noegel AA.
Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans.
Gene 279, 69-79 2001)

Glockner G, Szafranski K, Winckler T, Dingermann T, Quail MA, Cox E, Eichinger L, Noegel AA, Rosenthal A.
The complex repeats of Dictyostelium discoideum.
Genome Res. 11, 585-94 (2001).

Herr C, Smyth N, Ullrich S, Yun F, Sasse P, Hescheler J, Fleischmann B, Lasek K, Brixius K, Schwinger RH, Fassler R, Schroder R, Noegel AA.
Loss of annexin A7 leads to alterations in frequency-induced shortening of isolated murine cardiomyocytes.
Mol Cell Biol. 21, 4119-28 (2001).

Clemen CS, Herr C, Lie AA, Noegel AA, Schroder R.
Annexin VII: an astroglial protein exhibiting a Ca2+-dependent subcellular distribution.
Neuroreport 12, 1139-44 (2001).

Rivero F, Dislich H, Glockner G, Noegel AA.
The Dictyostelium discoideum family of Rho-related proteins.
Nucleic Acids Res 29, 1068-79 (2001).

Olski TM, Noegel AA, Korenbaum E.
Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily.
J Cell Sci. 114, 525-38 (2001).


Steinmetz MO, Hoenger A, Stoffler D, Noegel AA, Aebi U, Schoenenberger CA
Polymerization, three-dimensional structure and mechanical properties of dictyostelium versus rabbit muscle actin filaments.
J Mol Biol 303, 171-84 (2000).

Mohrs MR, Janssen KP, Kreis T, Noegel AA, Schleicher M
Cloning and characterization of beta-COP from Dictyostelium discoideum.
Eur J Cell Biol 79, 350-7 (2000).

Verzili D, Zamparelli C, Mattei B, Noegel AA, Chiancone E
The sorcin-annexin VII calcium-dependent interaction requires the sorcin N-terminal domain.
FEBS Lett 471, 197-200 (2000).

Lee SS, Karakesisoglou I, Noegel AA, Rieger D, Schleicher M
Dissection of functional domains by expression of point-mutated profilins in Dictyostelium mutants.
Eur J Cell Biol 79, 92-103 (2000)

Weiner OH, Alt M, Durr R, Noegel AA, Caselmann WH
Rapid and reproducible quantification of hepatitis C virus cDNA by fluorescence correlation spectroscopy.
Digestion 61, 84-9 (2000).

Clemen CS, Hofmann A, Zamparelli C, Noegel AA
Expression and localisation of annexin VII (synexin) isoforms in differentiating myoblasts.
J Muscle Res Cell Motil 20, 669-79 (1999)

Noegel AA, Schleicher M
The actin cytoskeleton of Dictyostelium: a story told by mutants.
J Cell Sci 113,759-66 (2000).

Szafranski K, Glockner G, Dingermann T, Dannat K, Noegel AA, Eichinger L, Rosenthal A, Winckler T
Non-LTR retrotransposons with unique integration preferences downstream of Dictyostelium discoideum tRNA genes.
Mol Gen Genet. 262, 772-80 (1999)

Fucini P, Koppel B, Schleicher M, Lustig A, Holak TA, Muller R, Stewart M, Noegel AA
Molecular architecture of the rod domain of the Dictyostelium gelation factor (ABP120).
J Mol Biol. 291, 1017-23 (1999)

Noegel AA, Rivero F, Albrecht R, Janssen KP, Kohler J, Parent CA, Schleicher M
Assessing the role of the ASP56/CAP homologue of Dictyostelium discoideum and the requirements for subcellular localization.
J Cell Sci. 112, 3195-203 (1999)

McCoy AJ, Fucini P, Noegel AA, Stewart M
Structural basis for dimerization of the Dictyostelium gelation factor (ABP120) rod.
Nat Struct Biol. 6, 836-41 (1999)

Rivero F, Furukawa R, Fechheimer M, Noegel AA
Three actin cross-linking proteins, the 34 kDa actin-bundling protein, alpha-actinin and gelation factor (ABP-120), have both unique and redundant roles in the growth and development of Dictyostelium.
J Cell Sci. 112, 2737-51 (1999)

Rivero F, Albrecht R, Dislich H, Bracco E, Graciotti L, Bozzaro S, Noegel AA
RacF1, a novel member of the Rho protein family in Dictyostelium discoideum, associates transiently with cell contact areas, macropinosomes, and phagosomes.
Mol Biol Cell. 10, 1205-19 (1999)

Karakesisoglou I, Janssen KP, Eichinger L, Noegel AA, Schleicher M.
Identification of a suppressor of the Dictyostelium profilin-minus phenotype as a CD36/LIMP-II homologue.
J Cell Biol. 145, 167-81 (1999).

Fulgenzi G, Graciotti L, Granata AL, Corsi A, Fucini P, Noegel AA, Kent HM, Stewart M.
Location of the binding site of the mannose-specific lectin comitin on F-actin.
J Mol Biol. 284, 1255-63 (1998).

Renner C, Baumgartner R, Noegel AA, Holak TA.
Backbone Dynamics of the CDK Inhibitor p19(INK4d) Studied by 15N NMR Relaxation Experiments at Two Field Strengths.
J Mol Biol. 283, 221-229 (1998).

Rivero F, Kuspa A, Brokamp R, Matzner M, Noegel AA.
Interaptin, an actin-binding protein of the alpha-actinin superfamily in Dictyostelium discoideum, is developmentally and cAMP-regulated and associates with intracellular membrane compartments.
J Cell Biol. 142, 735-50 1998).

Fisher PR, Noegel AA, Fechheimer M, Rivero F, Prassler J, Gerisch G.
Photosensory and thermosensory responses in Dictyostelium slugs are specifically impaired by absence of the F-actin cross-linking gelation factor (ABP-120).
Curr Biol. 7, 889-92 (1997).

Fucini P, McCoy AJ, Gomez-Ortiz M, Schleicher M, Noegel AA, Stewart M.
Crystallization and preliminary X-Ray diffraction characterization of a dimerizing fragment of the rod domain of the Dictyostelium gelation factor (ABP-120).
J Struct Biol. 120, 192-195 (1997).

Bracco E, Peracino B, Noegel AA, Bozzaro S.
Cloning and transcriptional regulation of the gene encoding the vacuolar/H+ ATPase B subunit of Dictyostelium discoideum.
FEBS Lett. 419, 37-40 (1997).

Liemann S, Bringemeier I, Benz J, Gottig P, Hofmann A, Huber R, Noegel AA, Jacob U.
Crystal structure of the C-terminal tetrad repeat from synexin (annexin VII) of Dictyostelium discoideum.
J Mol Biol. 270, 79-88 (1997).

Fucini P, Renner C, Herberhold C, Noegel AA, Holak TA.
The repeating segments of the F-actin cross-linking gelation factor (ABP-120) have an immunoglobulin-like fold.
Nat Struct Biol. 4, 223-230 (1997).

Kalus W, Baumgartner R, Renner C, Noegel A, Chan FK, Winoto A, Holak TA.
NMR structural characterization of the CDK inhibitor p19INK4d.
FEBS Lett 401, 127-132 (1997).

Rivero F, Koppel B, Peracino B, Bozzaro S, Siegert F, Weijer CJ, Schleicher M, Albrecht R, Noegel AA.
The role of the cortical cytoskeleton: F-actin crosslinking proteins protect against osmotic stress, ensure cell size, cell shape and motility, and contribute to phagocytosis and development.
J. Cell. Sci. 109, 2679-2691 (1996).

Rivero F, Furukawa R, Noegel AA, Fechheimer M.
Dictyostelium discoideum cells lacking the 34,000-dalton actin-binding protein can grow, locomote, and develop, but exhibit defects in regulation of cell structure and movement: a case of partial redundancy.
J. Cell Biol. 135, 965-980 (1996).

Schuster SC, Noegel AA, Oehme F, Gerisch G, Simon MI.
The hybrid histidine kinase DokA is part of the osmotic response system of Dictyostelium.
EMBO J. 15, 3880-3889 (1996).

Stoeckelhuber M, Noegel AA, Eckerskorn C, Kohler J, Rieger D, Schleicher M.
Structure/function studies on the pH-dependent actin-binding protein hisactophilin in Dictyostelium mutants
J. Cell. Sci. 109, 1825-1835 (1996)

Jung E, Fucini P, Stewart M, Noegel AA, Schleicher M.
Linking microfilaments to intracellular membranes: the actin-binding and vesicle-associated protein comitin exhibits a mannose-specific lectin activity.
EMBO J. 15, 1238-1246 (1996).

Andre B, Noegel AA, Schleicher M.
Dictyostelium discoideum contains a family of calmodulin-related EF-hand proteins that are developmentally regulated.
FEBS Lett. 382, 198-202 (1996).

Eichinger L, Koppel B, Noegel AA, Schleicher M, Schliwa M, Weijer K, Witke W, Janmey PA.
Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants.
Biophys. J. 70, 1054-1060 (1996).

Gottwald U, Brokamp R, Karakesisoglou I, Schleicher M, Noegel AA.
Identification of a cyclase-associated protein (CAP) homologue in Dictyostelium discoideum and characterization of its interaction with actin.
Mol. Biol. Cell 7, 261-272 (1996).

Janssen KP, Eichinger L, Janmey PA, Noegel AA, Schliwa M, Witke W, Schleicher M.
Viscoelastic properties of F-actin solutions in the presence of normal and mutated actin-binding proteins.
Arch. Biochem. Biophys. 325, 183-189 (1996).

Selbert S, Fischer P, Menke A, Jockusch H, Pongratz D, Noegel AA.
Annexin VII relocalization as a result of dystrophin deficiency.
Exp. Cell Res. 222, 199-208 (1996).

Noegel AA, Luna JE.
The Dictyostelium cytoskeleton.
Experientia 51, 1135-1143 (1995).

Behrisch A, Dietrich C, Noegel AA, Schleicher M, Sackmann E.
The actin-binding protein hisactophilin binds in vitro to partially charged membranes and mediates actin coupling to membranes.
Biochemistry 34, 15182-15190 (1995).

Schleicher M, Andre B, Andreoli C, Eichinger L, Haugwitz M, Hofmann A, Karakesisoglou J, Stockelhuber M, Noegel AA.
Structure/function studies on cytoskeletal proteins in Dictyostelium amoebae as a paradigm.
FEBS Lett. 369, 38-42 (1995).

Doring V, Veretout F, Albrecht R, Muhlbauer B, Schlatterer C, Schleicher M, Noegel AA.
The in vivo role of annexin VII (synexin): characterization of an annexin VII-deficient Dictyostelium mutant indicates an involvement in Ca(2+)-regulated processes.
J. Cell. Sci. 108, 2065-2076 (1995).

Fassler R, Pfaff M, Murphy J, Noegel AA, Johansson S, Timpl R, Albrecht R.
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts.
J. Cell Biol. 128, 979-988 (1995).

Selbert S, Fischer P, Pongratz D, Stewart M, Noegel AA.
Expression and localization of annexin VII (synexin) in muscle cells.
J. Cell. Sci. 108, 85-95 (1995).

Haugwitz M, Noegel AA, Karakesisoglou J, Schleicher M.
Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development.
Cell 79, 303-314 (1994).

Weiner OH, Murphy J, Griffiths G, Schleicher M, Noegel AA.
The actin-binding protein comitin (p24) is a component of the Golgi apparatus.
J. Cell Biol. 123, 23-34 (1993).

Haus U, Trommler P, Fisher PR, Hartmann H, Lottspeich F, Noegel AA, Schleicher M.
The heat shock cognate protein from Dictyostelium affects actin polymerization through interaction with the actin-binding protein cap32/34.
EMBO J. 12, 3763-3771 (1993).

Hofmann A, Noegel AA, Bomblies L, Lottspeich F, Schleicher M.
The 100 kDa F-actin capping protein of Dictyostelium amoebae is a villin prototype ('protovillin').
FEBS Lett. 328, 71-76 (1993)

Witke W, Hofmann A, Koppel B, Schleicher M, Noegel AA.
The Ca(2+)-binding domains in non-muscle type alpha-actinin: biochemical and genetic analysis.
J. Cell Biol. 121, 599-606 (1993).

Faix J, Gerisch G, Noegel AA.
Overexpression of the csA cell adhesion molecule under its own cAMP-regulated promoter impairs morphogenesis in Dictyostelium.
J. Cell. Sci. 102, 203-214 (1992).

Schleicher M, Noegel AA.
Dynamics of the Dictyostelium cytoskeleton during chemotaxis.
New Biol. 4, 461-472 (1992).

Witke W, Schleicher M, Noegel AA.
Redundancy in the microfilament system: abnormal development of Dictyostelium cells lacking two F-actin cross-linking proteins.
Cell 68, 53-62 (1992).

Haus U, Hartmann H, Trommler P, Noegel AA, Schleicher M.
F-actin capping by cap32/34 requires heterodimeric conformation and can be inhibited with PIP2.
Biochem. Biophys. Res. Commun. 181, 833-839 (1991).

Leiting B, Noegel AA.
The ble gene of Streptoalloteichus hindustanus as a new selectable marker for Dictyostelium discoideum confers resistance to phleomycin.
Biochem. Biophys. Res. Commun. 180, 1403-1407 (1991).

Haugwitz M, Noegel AA, Rieger D, Lottspeich F, Schleicher M.
Dictyostelium discoideum contains two profilin isoforms that differ in structure and function.
J. Cell. Sci. 100, 481-489 (1991).

Doring V, Schleicher M, Noegel AA.
Dictyostelium annexin VII (synexin). cDNA sequence and isolation of a gene disruption mutant.
J. Biol. Chem. 266, 17509-17515 (1991).

Wiesmuller L, Wittbrodt J, Noegel AA, Schleicher M.
Purification and cDNA-derived sequence of adenylosuccinate synthetase from Dictyostelium discoideum.
J. Biol. Chem. 266, 2480-2485 (1991).

Noegel AA, Schleicher M.
Phenotypes of cells with cytoskeletal mutations.
Curr. Opin. Cell Biol. 3, 18-26 (1991).

Eichinger L, Noegel AA, Schleicher M.
Domain structure in actin-binding proteins: expression and functional characterization of truncated severin.
J. Cell Biol. 112, 665-676 (1991)

Barisic K, Mollner S, Noegel AA, Gerisch G, Segall JE.
cDNA sequence of cyclophilin from Dictyostelium discoideum.
Dev Genet. 12, 50-3 (1991).

Gerisch G, Noegel AA, Schleicher M.
Genetic alteration of proteins in actin-based motility systems.
Annu Rev Physiol. 53, 607-28 (1991).

Brink M, Gerisch G, Isenberg G, Noegel AA, Segall JE, Wallraff E, Schleicher M.
A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor.
J Cell Biol. 111, 1477-89 (1990).

Faix J, Gerisch G, Noegel AA.
Constitutive overexpression of the contact site A glycoprotein enables growth-phase cells of Dictyostelium discoideum to aggregate.
EMBO J. 9, 2709-16 (1990).

Leiting B, Lindner IJ, Noegel AA.
The extrachromosomal replication of Dictyostelium plasmid Ddp2 requires a cis-acting element and a plasmid-encoded trans-acting factor.
Mol Cell Biol. 10, 3727-36 (1990).

Noegel AA, Gerisch G, Lottspeich F, Schleicher M.
A protein with homology to the C-terminal repeat sequence of Octopus rhodopsin and synaptophysin is a member of a multigene family in Dictyostelium discoideum.
FEBS Lett. 266, 118-22 (1990).

Wiesmuller L, Noegel AA, Barzu O, Gerisch G, Schleicher M.
cDNA-derived sequence of UMP-CMP kinase from Dictyostelium discoideum and expression of the enzyme in Escherichia coli.
J Biol Chem. 265, 6339-45 (1990).

Gurniak CB, Bang AG, Noegel AA.
Transcript and sequence analysis of a 5.1 kb contiguous fragment of Dictyostelium discoideum plasmid Ddp1 that contains the origin of replication and codes for several transcripts.
Curr Genet. 17, 321-5 (1990).

Bomblies L, Biegelmann E, Doring V, Gerisch G, Krafft-Czepa H, Noegel AA, Schleicher M, Humbel BM.
Membrane-enclosed crystals in Dictyostelium discoideum cells, consisting of developmentally regulated proteins with sequence similarities to known esterases.
J Cell Biol. 110, 669-79 (1990).

Witke W, Noegel AA.
A single base exchange in an intron of the Dictyostelium discoideum alpha-actinin gene inhibits correct splicing of the RNA but allows transport to the cytoplasm and translation.
J Biol Chem. 265, 34-9 (1990).

Schleicher M, Eichinger L, Witke W, Noegel AA.
Ca2(+)-binding proteins as components of the cytoskeleton.
Adv Exp Med Biol. 269, 99-102 (1990).

Hartmann H, Schleicher M, Noegel AA.
Heterodimeric capping proteins constitute a highly conserved group of actin-binding proteins.
Dev Genet. 11, 369-76 (1990).

Harloff C, Gerisch G, Noegel AA.
Selective elimination of the contact site A protein of Dictyostelium discoideum by gene disruption.
Genes Dev. 3, 2011-9 (1989).

Schulze H, Huckriede A, Noegel AA, Schleicher M, Jockusch BM.
Alpha-actinin synthesis can be modulated by antisense probes and is autoregulated in non-muscle cells.
EMBO J. 8, 3587-93 (1989).

Noegel AA, Rapp S, Lottspeich F, Schleicher M, Stewart M.
The Dictyostelium gelation factor shares a putative actin binding site with alpha-actinins and dystrophin and also has a rod domain containing six 100-residue motifs that appear to have a cross-beta conformation.
J Cell Biol. 109, 607-18 (1989).

Hartmann H, Noegel AA, Eckerskorn C, Rapp S, Schleicher M.
Ca2+-independent F-actin capping proteins. Cap 32/34, a capping protein from Dictyostelium discoideum, does not share sequence homologies with known actin-binding proteins.
J Biol Chem. 264, 12639-47 (1989).

Sandholzer U, Centea-Intemann M, Noegel AA, Lottspeich F.
cDNA and derived amino acid sequence of the hypusine containing protein from Dictyostelium discoideum.
FEBS Lett. 246, 94-100 (1989).

Muller-Taubenberger A, Westphal M, Noegel A, Gerisch G.
A developmentally regulated gene product from Dictyostelium discoideum shows high homology to human alpha-L-fucosidase.
FEBS Lett. 246, 185-92 (1989).

Andre E, Brink M, Gerisch G, Isenberg G, Noegel A, Schleicher M, Segall JE, Wallraff E.
A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis.
J Cell Biol. 108, 985-95 (1989).

Scheel J, Ziegelbauer K, Kupke T, Humbel BM, Noegel AA, Gerisch G, Schleicher M.
Hisactophilin, a histidine-rich actin-binding protein from Dictyostelium discoideum. J Biol Chem. 264, 2832-9 (1989).

Noegel AA, Leiting B, Witke W, Gurniak C, Harloff C, Hartmann H, Wiesmuller E, Schleicher M.
Biological roles of actin-binding proteins in Dictyostelium discoideum examined using genetic techniques.
Cell Motil Cytoskeleton. 14, 69-74 (1989).

Noegel AA, Witke W.
Inactivation of the alpha-actinin gene in Dictyostelium.
Dev Genet. 9, 531-8 (1988).

Schleicher M, Andre E, Hartmann H, Noegel AA.
Actin-binding proteins are conserved from slime molds to man.
Dev Genet. 9, 521-30 (1988).

Muller-Taubenberger A, Hagmann J, Noegel A, Gerisch G.
Ubiquitin gene expression in Dictyostelium is induced by heat and cold shock, cadmium, and inhibitors of protein synthesis.
J Cell Sci. 90, 51-8 (1988).

Muller-Taubenberger A, Westphal M, Jaeger E, Noegel A, Gerisch G.
Complete cDNA sequence of a Dictyostelium ubiquitin with a carboxy-terminal tail and identification of the protein using an anti-peptide antibody.
FEBS Lett. 229, 273-8 (1988).

Wagle G, Noegel A, Scheel J, Gerisch G.
Phosphorylation of threonine residues on cloned fragments of the Dictyostelium myosin heavy chain.
FEBS Lett. 227, 71-5 (1988).

Andre E, Lottspeich F, Schleicher M, Noegel A.
Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains.
J Biol Chem. 263, 722-7 (1988).

Noegel AA, Witke W.
Inactivation of the alpha-actinin gene in Dictyostelium.
Dev Genet. 9, 531-8 (1988).

Witke W, Nellen W, Noegel A.
Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein.
EMBO J. 6(13), 4143-8 (1987).

Noegel A, Witke W, Schleicher M.
Calcium-sensitive non-muscle alpha-actinin contains EF-hand structures and highly conserved regions.
FEBS Lett. 221, 391-6 (1987).

Witke W, Schleicher M, Lottspeich F, Noegel A.
Studies on the transcription, translation, and structure of alpha-actinin in Dictyostelium discoideum.
J Cell Biol. 103, 969-75 (1986).

Welker DL, Hirth KP, Romans P, Noegel A, Firtel RA, Williams KL.
The use of restriction fragment length polymorphisms and DNA duplications to study the organization of the actin multigene family in Dictyostelium discoideum
Genetics. 112, 27-42 (1986)

Noegel A, Welker DL, Metz BA, Williams KL.
Presence of nuclear associated plasmids in the lower eukaryote Dictyostelium discoideum
J Mol Biol. 185, 447-50 (1985)

Noegel A, Gotschlich EC.
Isolation of a high molecular weight polyphosphate from Neisseria gonorrhoeae
J Exp Med. 157, 2049-60 (1983)

Noegel A, Rdest U, Goebel W.
Determination of the functions of hemolytic plasmid pHly152 of Escherichia coli
J Bacteriol. 145, 233-47 (1981)

Noegel A, Rdest U, Springer W, Goebel W.
Plasmid cistrons controlling synthesis and excretion of the exotoxin alpha-haemolysin of Escherichia coli
Mol Gen Genet. 175, 343-50 (1979)