Institut für Biochemie II   Printer friendly
Publications



2016

 

Ali, N.J., Dias Gomes, M., Bauer, R., Brodesser, S., Niemann, C., and Iden, S. (2016) Essential role of polarity protein Par3 for epidermal homeostasis through regulation of barrier function, keratinocyte differentiation, and stem cell maintenance. J. Invest. Dermatol. 136, 2406-2416.

 

Barrera-Ocampo, A., Arlt, S., Matschke, J., Hartmann, U., Puig, B., Ferrer, I., Zürbig, P., Glatzel, M., Sepulveda-Falla, D., and Jahn, H. (2016) Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease. J Neuropathol Exp Neurol. 75, 903-916.

 

Brady, J.J., Chuang, C.H., Greenside, P.G., Rogers, Z.N., Murray, C.W., Caswell, D.R., Hartmann, U., Connolly, A.J., Sweet-Cordero, E.A., Kundaje, A., and Winslow, M.M. (2016) An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency. Cancer Cell. 29, 697-710.

 

Breloy I., Schwientek, T., Althoff, D., Holz, M., Koppen, T., Krupa, S., and Hanisch F.G. (2016) Functional analysis of the glucuronyltransferases GlcAT-P and GlcAT-S of Drosophila melanogaster: Distinct activities towards the O-linked T-antigen. Biomolecules 6, 8.

 

Bultmann-Mellin, I., Essers, J., van Heijingen, P.M., von Melchner, H., Sengle, G., and Sterner-Kock, A. (2016) Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice. Dis Model Mech. 9, 1367-1374.

 

Carrion, D.C., Korkmaz, Y., Cho, B., Kopp, M., Bloch, W., Addicks, K., and Niedermeier, W. (2016) Loss of Aβ-nerve endings associated with the Merkel cell-neurite complex in the lesional oral mucosa epithelium of lichen planus and hyperkeratosis. Int. J. Oral. Sci. 30, 32-38.

 

Chalick, M., Jacobi, O., Pichinuk, E., Garbar, C., Bensussan, A., Meeker, A., Ziv, R., Zehavi, T., Smorodinsky, N.I., Hilkens, J., Hanisch, F.G., Rubinstein, D.B., and Wreschner, D.H. (2016) MUC1-ARF-A novel MUC1 protein that resides in the nucleaus and is expressed by alternative reading frame translation of MUC1 mRNA. PLoS One 11, e0165031.

 

Florea, F., Koch, M., Hashimoto, T., and Sitaru, C. (2016) Autoimmunity against laminins. Clin. Immunol. 170, 39-52.

 

Gebauer, J.M., Kobbe, B., Paulsson, M., and Wagener, R. (2016) Structure, evolution and expression of collagen XXVIII: Lessons from the zebrafish. Matrix Biol. 49, 106-119.

 

Gerin, I., Ury, B., Breloy, I., Bouchet-Seraphin, C., Boisee, J., Halbout, M., Graff, J., Vertommen, D., Muccioloi, G.G., Seta, N., Cuisset, J.M., Dabaj, I., Quijano-Roy, S., Grahn, A., Van Scahftingen, E., and Bommer, G.T. (2016) ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto -dystroglycan. Nat. Commun. 7, 11534.

 

Grandin, M., Meier, M., Delcros, J.G., Nikodemus, D., Reuten, R., Patel, T.R., Goldschneider, D., Orriss, G., Krahn, N., Boussouar, A., Abes, R., Dean, Y., Neves, D., Bernet, A., Depil, S., Schneiders, F., Poole, K., Dante, R., Koch, M., Mehlen, P., and Stetefeld, J. (2016) Structural decoding of the netrin-1/UNC5 interaction and its therapeutical implications in cancer. Cancer Cell 29, 173-185.

 

Heilig, J., Paulsson, M., and Zaucke, F. (2016) Insulin-like growth factor 1 receptor (IGF1R) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification. Bone 83, 48-57.

 

Izu, Y., Ezura, Y., Koch, M., Birk, D.E., and Noda, M. (2016) Collagens VI and XII form complexes mediating osteblast interactions during osteogenesis. Cell Tissue. Res. 364, 623-635.

 

Kamper, M., Hamman, N., Prein, C., Clausen-Schumann, H., Farkas, Z., Aszodi, A., Niehoff, A., Paulsson, M., and Zaucke, F. (2016) Early changes in morphology, bone mineral density and matrix composition of vertebrae lead to disc degeneration in aged collagen IX -/- mice. Matrix Biol. 49, 132-143.

 

Knebel-Mörsdorf, D. (2016) Nectin-1 and HVEM: cellular receptors for HSV-1 in skin. Oncotarget 7, 19087-19088.

 

Kociok, N., Crespo-Garcia, S., Liang, Y., Klein, S.V., Nürnberg, C., Reichhart, N., Skozyrski, S., Moritz, E., Maier, A.K., Brunken, W.J., Strauß, O., Koch, M., and Joussen, A.M. (2016) Lack of netrin-4 modulates pathologic neovascularization in the eye. Sci. Rep. 6, 18828.

 

Kreft, S., Klatt, A.R., Straßburger, J., Pöschl, E., Flower, R.J., Eming, S., Reutelingsperger, B., Brisson, A., and Brachvogel, B. (2016) Skin wound repair is not altered in the absence of endogenous AnxA1 or AnxA5, but pharmacological concentrations of AnxA4 and AnxA5 inhibit wound hemostasis. Cells Tissues Organs 201, 287-298.

 

Leite Dantas, R., Masemann, D., Schied, T., Bergmeier, V., Vogl, T., Loser, K., Brachvogel, B., Varga, G., Ludwig, S., and Wixler, V. (2016) Macrophage-mediated psoriasis can be suppressed by regulatory T lymphocytes. J. Pathol. 240, 366-377.

 

Maaß, T., Bayley, C.P., Mörgelin, M., Lettmann, S., Bonaldo, P., Paulsson, M., Baldock, C., and Wagener, R. (2016) Heterogeneity of collagen VI microfibrils: Structural analysis of non-collagenous regions. J. Biol. Chem. 291, 5247-5258.

 

Oecal, S., Socher, E., Uthoff, M., Ernst, C., Zaucke, F., Sticht, H., Baumann, U., and Gebauer, J.M. (2016) The pH-Dependent Client Release From the Collagen-Specific Chaperone Hsp47 is Triggered by a Tandem Histidine Pair. J. Biol. Chem. 291, 12612-12626.

 

Park, J., Yu, Y.P., Zhou, C., Li, K.W., Wang, D., Chang, E., Kim, D.S., Vo, B., Zhang, X., Gong, N., Sharp, K., Steward, O., Vitko, I., Perez-Reyes, E., Wang, F., Eroglu, C., Barres, B., Zaucke, F., Feng, G., and Luo, Z.D. (2016) Central mechansims mediating thrombospondin-4 induced pain states. J. Biol. Chem. 291, 13335-13348.

 

Peters, U., Solominidou, E., Korkmaz, Y., Rüttermann, S., Klocke, A., Flemmig, T.F., and Beikler, F. (2016) Regulator of Calcineurin 1 in Periodontal Disease. Mediators Inflamm. 2016, 5475821

 

Patel, T.R., Nikodemus, D., Besong, T.M., Reuten, R., Meier, M., Harding, S.E., Winzor, D.J., Koch, M., and Stetefeld, J. (2016) Biophysical analysis of a lethel laminin alpha-1 mutation reveals altered self-interaction. (2016) Matrix Biol. 49, 93-105.

 

Pilecki, B., Holm, A.T., Schlosser, A., Moeller, J.B., Wohl, A.P., Zuk, A.V., Heumüller, S.E., Wallis, R., Moestrup, S.K., Sengle, G., Holmskov, U., and Sorensen, G.L. (2016) Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation. J Biol Chem. 291, 1103-1114.

 

Pitzler, L., Auler, M., Probst, K., Frie, C., Bergmeier, V., Holzer, T., Belluoccio, D., Van den Bergen, J., Etich, J., Ehlen, H., Zhou, Z., Bielke, W., Pöschl, E., Paulsson, M., and Brachvogel, B. (2016) miR-126-3p promotes matrix-dependent perivascular cell attachment, migration and intercellular interaction. Stem Cells 34, 1297-1309.

 

Reuten, R., Nikodemus, D., Oliveira, M.B., Patel, T.R., Brachvogel, B., Breloy I., Stetefeld, J., and Koch, M. (2016) Maltose-binding protein (MBP), a secretion-enhancing tag for mamallian protein expression systems. PLoS One 11, e0152386.

 

Reuten, R., Patel, T.R., McDougall, M., Rama, N., Nikodemus, D., Gibert, B., Delcros, J.G., Prein, C., Meier, M., Metzger, S., Zhou, Z., Kaltenberg, J., McKee, K.K., Bald, T., Tüting, T., Zigrino, P., Dionov, V., Bloch, W., Clausen-Schaumann, H., Pöschl, E., Yurchenco, P., Ehrbar, M., Meheln, P., Stetefeld, J., and Koch, M. (2016) Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes. Nat. Commun. 7, 13515.

 

Sabatelli, P., Sardone, F., Traina, F., Merlini, L., Santi, S., Wagener, R., and Faldini, C. (2016). TGF-β1 differentially modulates the collagen VI α5 and α6 chains in human tendon cultures. J. Biol. Regul. Homeost. Agents. 30, 107-113

 

Sardone, F., Santi, S., Tagliavini, F., Traina, F., Merlini, L., Squarzoni, S., Cescon, M., Wagener, R., Maraldi, N.M., Bonaldo, P., Faldini, C., and Sabatelli, P. (2016) Collagen VI-NG2 axis in human tendon fibroblasts under conditions mimicking injury response. Matrix Biol. 55, 90-105.

 

Sasaki, T., Hanisch, F.G, Deutzmann, R., Sakai, L.Y., Sakuma, T., Miyamoto, T., Yamamoto, T., Hannappel, E., Chu, M.L., Lanig, H., and von der Mark, K. (2016) Functional consequences of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa. Matrix Biol. 56, 132-149.

 

Schiavinato, A., Keene, D.R., Wohl, A.P., Corallo, D., Colombatti, A., Wagener, R., Paulsson, M., Bonaldo, P., and Sengle, G. (2016) Targeting of EMILIN-1 and EMILIN-2 to fibrillin microfibrils facilitates their incorporation into the extracellular matrix. J. Invest. Dermatol., 136, 1150-1160.

 

Scholz, P., Auler, M., Brachvogel, B., Benzing, T., Mallmann, P., Streichert, T., and Klatt, A.R. (2016) Detection of multiple annexin autoantobodies in a patient with recurrent miscarriages, fulminant stroke and seronegative antiphospholipid syndrome. Biochem. Med. (Zagreb) 26, 272-278.

 

Schroten, H., Hanisch, F.G., and Hansmann, G.S. (2016) Human norovirus interactions with histo-blood group antigens and human milk oligosaccharides. J. Virol. 90, 5855-5859.

 

Schulz, J.-N., Nüchel, J., Niehoff, A., Bloch, W., Schönborn, K., Hayashi, S., Kamper, M., Brinckmann, J., Plomann, M., Paulsson, M., Krieg, T., Zaucke, F., and Eckes, B. (2016) COMP-assisted collagen secretion – a novel intracellular function required for fibrosis. J. Cell Sci. 129, 706-716.

 

Staubach, S., Pekmez, M., and Hanisch, F.G. (2016) Differential proteomics of urinary exovesicles from classical galactosemic patients reveals subclinical kidney insufficiency. J. Proteome Res. 15, 1754-1761.

 

Steiger, J., Stephan, A., Inkeles, M.S., Realegeno, S., Bruns, H., Kröll, P., de Castro Kroner, J., Sommer, A., Batinica, M., Pitzler, L., Kalscheuer, R., Hartmann, P., Plum, G., Stenger, S., Pellegrini, M., Brachvogel, B., Modlin, R., and Fabri, M. (2016) Imatinib triggers phagolysosome acidification and antimicrobial activity against Mycobacterium bovis Bacille Calmette-Guerin in glucocorticoid-treated human macrophages. J. Immunol. 197, 222-232.

 

Stephan, A., Batinicy, M., Steiger, J., Hartmann, P., Zaucke, F., Bloch, W., and Fabri, M. (2016) LL37:DNA complexes provide antimicrobial activity against intracellular bacteria in human macrophages. Immunology 148, 420-432.

 

Stoffel, W., Hammels, I., Jenke, B., Binczek, E., Schmidt-Soltau, I., Brodesser, S., Schauss, A., Etich, J., Heilig, J., and Zaucke, F. (2016) Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition. Cell Death Dis. 7, e2488.

 

Troilo, H., Barrett, A.L., Zuk, A.V., Lockhart-Cairns, M.P., Wohl, A.P., Bayley, C.P., Dajani, R., Tunnicliff, R.B., Green, L., Jowitt, T.A., Sengle, G., and Baldock, C. (2016) Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway. Matrix Biol. 55, 49-62.

 

Uckelmann, H., Blaszkiewics, S., Nicolae, C., Haas, S., Schnell, A., Wurzer, S., Wagener, R., Aszodi, R., and Essers, M.A. (2016) Extracellular matrix protein matrilin-4 regulates stress-induced HSC cell proliferation via CXCR4. J. Exp. Med. 213, 1961-1971.

 

Vihar, B., Hanisch, F.G., and Baumgartner, W. (2016) Neutral glycans from sandfish skin can reduce friction of polymers. J. R. Soc. Interface 13, pii: 20160103.

 

Wohl, A.P., Troilo, H., Collins, R.F., Baldock, C., and Sengle, G. (2016) Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1. J Biol Chem. 291, 12732-12746.

 

Zhou, Z., Pausch, F., Schlötzer-Schrehardt, U., Brachvogel, B., and Pöschl, E. (2016) Induction of initial steps of angiogenic differentiation and maturation of endothelial cells by pericytes in vitro and the role of collagen IV. Histchem. Cell Biol. 145, 511-525.

 

 



09 März 2017
Zentrum für Biochemie, Joseph-Stelzmann-Straße 52, D50931 Köln
Kritik und Anregungen: Gudrun Konertz
Telefon: +49-221-478-32743
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