Bad news: The Wisconsin Package can still be used "as is" at the "gendb" server. The existing databases that are still maintained are given in the banner of the package during activation. It could be accessed only within the university. It is not more supported by Accelrys, the company that bought it lately. The local database at the RRZK is also provided "as is" the last time it was updated.

Sequence Databases
Information on the databases is available in EMBL Release Notes about the quarterly updated full release of the EMBL DNA and Swiss Protein Databases. New sequences between the releases are added daily to the 'emblnew' database. Furthermore, the Protein Data Bank (PDB) offers important information on 3D structures of many proteins and DNA molecules. Its feature tables give information on features joinly defined by the DDBJ, EMBL, and the GenBank

W2H!!!
Do you prefer a windows environment for your work? Using a browser to access the program is also possible (University of Cologne only). This interface was written by Martin Senger, German Cancer Research Center (DKFZ) in Heidelberg.

The interactive Wisconsin Package™ Tutorial (WisPacT) has two goals in mind.

During the genetic practical course for advanced biology students they have to learn the basics techniques in sequence analysis. It begins with an autoradiograph of a DNA sequence, going the whole way from the DNA sequence to a possible three dimensional structure of the protein.

On the other hand, bench workers need a practical tool in the lab that is able to help them immediately solving questions in sequence analysis arising during their experiments.

Beside a basic unix knowledge and the learning of basic syntax of the Wisconsin Package, the primary method used in this course consists of "Learning by Doing". The interactive access is open for local user. To work on the gendb server you will need an ssh client that can be downloaded from the RRZK.

Amino Acid Information:
General information, chemical properties, suggested amino acid substitutions, structural, and genetic properties.