Gruppe Hussain  
Publikationen


  1. CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly.
    Sukumaran SK, Stumpf M, Salamon S, Ahmad I, Bhattacharya K, Fischer S, Müller R, Altmüller J, Budde B, Thiele H, Tariq M, Malik NA, Nürnberg P, Baig SM, Hussain MS, Noegel AA.
    Mol Genet Genomics 292, 365-383 (2017)

  2. Genetic heterogeneity in Pakistani microcephaly families revisited.
    Ahmad I, Baig SM, Abdulkareem AR, Hussain MS, Sur I, Toliat MR, Nürnberg G, Dalibor N, Moawia A, Waseem SS, Asif M, Nagra H, Sher M, Khan MMA, Hassan I, Rehman SU, Thiele H, Altmüller J, Noegel AA, Nürnberg P.
    Clin Genet. 92, 62-68 (2017)

  3. A novel homozygous splicing mutation of CASC5 causes primary microcephaly in a large Pakistani family.
    Szczepanski S, Hussain MS, Sur I, Altmüller J, Thiele H, Abdullah U, Waseem SS, Moawia A, Nürnberg G, Noegel AA, Baig SM, Nürnberg P.
    Hum Genet. 135, 157-70 (2016)

  4. The centrosomal component CEP161 of Dictyostelium discoideum interacts with the Hippo signaling pathway.
    Sukumaran SK, Blau-Wasser R, Rohlfs M, Gallinger C, Schleicher M, Noegel AA.
    Cell Cycle. 14, 1024-35 (2015)

  5. Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy.
    Martin CA, Ahmad I, Klingseisen A, Hussain MS, Bicknell LS, Leitch A, Nürnberg G, Toliat MR, Murray JE, Hunt D, Khan F, Ali Z, Tinschert S, Ding J, Keith C, Harley ME, Heyn P, Müller R, Hoffmann I, Daire VC, Dollfus H, Dupuis L, Bashamboo A, McElreavey K, Kariminejad A, Mendoza-Londono R, Moore AT, Saggar A, Schlechter C, Weleber R, Thiele H, Altmüller J, Höhne W, Hurles ME, Noegel AA, Baig SM, Nürnberg P, Jackson AP.
    Nat Genet. Oct 26. doi: 10.1038/ng.3122 (2014)

  6. Mutations in CKAP2L, the Human Ortholog of the Mouse Radmis Gene, Cause Filippi Syndrome.
    Hussain MS, Battaglia A, Szczepanski S, Kaygusuz E, Toliat MR, Sakakibara S, Altmüller J, Thiele H, Nürnberg G, Moosa S, Yigit G, Beleggia F, Tinschert S, Clayton-Smith J, Vasudevan P, Urquhart JE, Donnai D, Fryer A, Percin F, Brancati F, Dobbie A, Smigiel R, Gillessen-Kaesbach G, Wollnik B, Noegel AA, Newman WG, Nürnberg, P.
    Am. J. Hum. Genet 95, 622-632 (2014)

  7. A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family.
    Khan MA, Rupp VM, Orpinell M, Hussain MS, Altmüller J, Steinmetz MO, Enzinger C, Thiele H, Höhne W, Nürnberg G, Baig SM, Ansar M, Nürnberg P, Vincent JB, Speicher MR, Gönczy P, Windpassinger C.
    Hum Mol Genet. Jun 20. pii: ddu318 (2014)

  8. CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly.
    Hussain MS, Baig SM, Neumann S, Peche VS, Szczepanski S, Nürnberg G, Tariq M, Jameel M, Naeem T, Fatima A, Malik NA, Ahmad I, Altmüller J, Frommolt P, Thiele H, Höhne W, Yigit G, Wollnik B, Nürnberg P, Noegel AA.
    Hum. Mol. Genet. 22, 5199-214 (2013)

  9. Meeting Report–Building a Centrosome
    Alexandre D. Baffet, Carol-Anne Martin, Ilaria Scarfone, Owen M. Daly, Ahuvit David, Alexandra Tibelius, Ramona Lattao, Muhammad S. Hussain and Jeffrey B. Woodruff.
    Journal of Cell Science 126, 3259–3262 (2013)

  10. Genetic heterogeneity in Pakistani microcephaly families.
    Hussain MS , Muhammad F, Bakhtiar SM, Inayat IA, Janzen E, Toliat MR, Eiberg H, Kjaer KW, Tommerup N, Noegel AA, Nürnberg P, Baig SM, Hansen L.
    Clinical Genetics 83, 446-51 (2012)

  11. A Truncating Mutation of CEP135 is associated with primary microcephaly and disturbed centrosomal function.
    Hussain M.S, Baig S.M, Neumann S, Nürnberg G, Farooq M, Ahmad I, Wajid M, Alef T, Hennies H-C, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel A.A, Nürnberg P.
    Am. J. Hum. Genet. 90, 871–8 (2012)

  12. ß-Thalassemia in Pakistan: a pilot program on prenatal diagnosis in Multan.
    Mahmood Baig S, Sabih D, Rahim MK, Azhar A, Tariq M, Sajid Hussain M, Saqlan Naqvi SM, Raja GK, Khan TN, Jameel M, Iram Z, Noor S, Baig UR, Qureshi JA, Baig SA, Bakhtiar SM.
    J Pediatr Hematol Oncol. 34, 90-2 (2012)

  13. A specific interaction between a novel variant in the cis-acting sonic hedgehog regulatory sequence (ZRS) and transcription factor and its association with preaxial polydactyly with triphalangeal thumb.
    Farooq, M., Troelsen, J., Boyd, M., Eiberg, H., Hansen L., Hussain, M.S., Rehman S., Azhar A., Bakhtiar S.M., Ali A., Tommerup, N., Kjaer, K.W., Baig, S.M.
    European Journal of Human Genetics. 18, 733–736 (2010)

  14. Seeing Clearly: The Dominant and Recessive Nature of FOXE3 in Eye Developmental Anomalies.
    Sibel Ugur Iseri, Robert J. Osborne, Martin Farrall, Alexander William Wyatt, Ghazala Mirza, Gudrun Nu¨ rnberg, Christian Kluck, Helen Herbert,6 Angela Martin, Muhammad Sajid Hussain, J. Richard O. Collin, Mark Lathrop, Peter Nürnberg, Jiannis Ragoussis, and Nicola K. Ragge.
    Human Mutation. 30, 1378–1386(2009)

  15. Compound heterozygous ASPM mutations in Pakistani MCPH families.
    Muhammad F, Mahmood Baig S, Hansen L, Sajid Hussain M, Anjum Inayat I, Aslam M, Anver Qureshi J, Toilat M, Kirst E, Wajid M, Nürnberg P, Eiberg H, Tommerup N, Kjaer KW.
    American Journal of Medical Genetics A. 149A, 926-30 (2009)

  16. Prevention of ß-thalassaemia in a large Pakistani family through cascade testing.
    Baig, S.M., Din, M.A., Hassan, H., Baig, J.M., Azhar, A., Aslam, M., Farooq, M., Hussain, M.S., Rasool, M., Anjum, I., Nawaz, S., Qureshi, J.A., Zaman, T.
    Community Genetics. 11, 68-70 (2008)



08 August 2017
Muhammad Sajid Hussain
Institute for Biochemistry I, Joseph-Stelzmann-Strasse 52, D50931 Cologne
Suggestions and wishes: Gudrun Konertz
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