Mörsdorf group  
Publications


  1. Thier K, Petermann P, Rahn E, Rothamel D, Bloch W, Knebel-Mörsdorf D. 2017.
    Mechanical barriers restrict invasion of herpes simplex virus 1 into human oral mucosa.
    J. Virol. Accepted manuscript posted online 6 September 2017, doi:10.1128/JVI.01295-17

  2. Rahn E, Thier K, Petermann P, Röbsam M, Staeheli P, Iden S, Niessen CM, and Knebel-Mörsdorf D. 2017.
    Epithelial barriers in murine skin during herpes simplex virus 1 infection: The role of tight junction formation.
    J. Invest. Dermatol. 137, 884-893

  3. Knebel-Mörsdorf, D. 2016.
    Nectin-1 and HVEM: cellular receptors for HSV-1 in skin.
    Oncotarget, DOI: 10.18632/oncotarget.8340

  4. Petermann P, Rahn E, Thier K, Hsu MJ, Rixon FJ, Kopp SJ, and Knebel-Mörsdorf D. 2015.
    Role of nectin-1 and HVEM as cellular receptors for herpes simplex virus 1 on primary murine dermal fibroblasts.
    J. Virol. 89, 9407-9416

  5. Rahn E, Petermann P, Thier K, Bloch W, Morgner J, Wickström SA, and Knebel-Mörsdorf D. 2015.
    Invasion of herpes simplex virus type 1 into murine epidermis: an ex vivo infection study.
    J. Invest. Dermatol. 135, 3009-3016

  6. Rahn E, Thier K, Petermann P, and Knebel-Mörsdorf D. 2015.
    Ex vivo infection of murine epidermis with herpes simplex virus type 1.
    J. Vis. Exp., e53046

  7. Petermann, P., Thier, K., Rahn, E., Rixon, F.J., Bloch, W., Özcelik, S., Krummenacher, C., Barron, M.J., Dixon, M.J., Scheu, S., Pfeffer, K. and Knebel-Mörsdorf, D. 2015.
    Entry mechanisms of Herpes Simplex Virus Type 1 into murine epidermis: Involvement of nectin-1 and HVEM as cellular receptors.
    J. Virol. 89, 262-274.

  8. Mainz, D., Quadt, I., Stranzenbach, A. K., Voss, D., Guarino, L. A., and Knebel-Mörsdorf, D. 2014.
    Expression and nuclear localization of the TATA-box-binding protein during baculovirus infection.
    J. gen Virol. 95, 1396-1407

  9. Rahn, E., Petermann, P., Hsu, M.-J., Rixon, F.J., and Knebel-Mörsdorf, D. 2011.
    Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent.
    PLoS ONE 6 (10):e25464. doi:10. 1371/journal. pone. 0025464

  10. Jaeger, V., Hoppe, S., Petermann, P., Liebig, T., Jansen, M. K., Renné, T., and Knebel-Mörsdorf, D. 2010.
    Herpes simplex virus type 1 entry into epithelial MDCKII cells: Role of VASP activities.
    J. gen Virol. 91, 2152-2157

  11. Petermann, P., Haase, I. and Knebel-Mörsdorf, D. 2009
    Impact of Rac1 and Cdc42 signaling during early Herpes simplex virus type 1 infection of keratinocytes.
    J. Virol. 83, 9759-9772

  12. Quadt, I., van Lent, J. W. M., and Knebel-Mörsdorf, D. 2007
    Studies of the silencing of baculovirus DNA binding protein.
    J. Virol. 81, 6122-6127

  13. Hoppe, S., Schelhaas, M., Jaeger, V., Liebig, T., Petermann, P., and Knebel-Mörsdorf, D. 2006
    Early herpes simplex virus type 1 infection is dependent on regulated Rac1/Cdc42 signalling in epithelial MDCKII cells.
    J. gen Virol. 87, 3483-3494

  14. Knebel-Mörsdorf, D., Quadt, I., Yi, L., Montier, L., and Guarino, L. 2006
    Expression of baculovirus late and very late genes depends on lef-4, a component of the viral RNA polymerase whose guanyltransferase function is essential.
    J. Virol. 80, 4168-4173

  15. Quadt, I., Günther, A. K., Voß, D., Schelhaas, M., and Knebel-Mörsdorf, D. 2006
    TATA-binding protein and TBP-associated factors during herpes simplex virus type 1 infection: Localization at viral DNA replication sites.
    Virus Res. 115, 207-213

  16. Schelhaas, M., Jansen, M., Haase, I., and Knebel-Mörsdorf, D. 2003
    Herpes simplex virus type 1 exhibits a tropism for basal entry in polarized epithelial cells.
    J. gen Virol. 84, 2473-2484

  17. Quadt, I., Mainz, D., Mans, R. M., Kremer, A., and Knebel-Mörsdorf, D. 2002
    Baculovirus infection raises the level of TATA-binding protein that colocalizes with viral DNA replication sites.
    J. Virol.76, 11123-11127

  18. Mainz, D., Quadt, I., and Knebel-Mörsdorf, D. 2002
    Nuclear IE2 structures are related to viral DNA replication sites during baculovirus infection.
    J. Virol., 76, 5198-5207

  19. Murges, D., Quadt, I., Schröer, J., and Knebel-Mörsdorf, D. 2001
    Dynamic nuclear localization of the baculovirus proteins IE2 and PE38 during the infection cycle: The promyelocytic leukemia protein colocalizes with IE2.
    Exp. Cell Res. 264, 219-232.

  20. Dreschers, S., Roncarati, R., and Knebel-Mörsdorf, D. 2001
    The actin rearrangement inducing factor of baculoviruses is tyrosine-phosphorylated and colocalizes to F-actin at the plasma membrane.
    J. Virol., 75, 3771-3778.

  21. Mans, R. M. W., and Knebel-Mörsdorf, D. 1999
    Mitochondrial DNA acts as a potential promoter of the baculovirus-induced RNA polymerase.
    Biological Chemistry, 380, 579-583

  22. Knebel-Mörsdorf, D., Kremer, A., Roncarati, R., Murges, D., Dreschers, S., and Quadt, I. 1999
    The role of early virus genes during the AcMNPV infection cycle.
    RIKEN review, Vol. 22:22-25

  23. Mans, R. M. W., and Knebel-Mörsdorf, D.1998
    In vitro transcription of pe38/polyhedrin hybrid promoters reveals sequences essential for recognition by the baculovirus-induced RNA polymerase and for the strength of very late promoters.
    J. Virol., 72:2991-2998

  24. Kremer, A., and Knebel-Mörsdorf, D. 1998
    The early baculovirus he65 promoter: On the mechanism of transcriptional activation by IE1.
    Virology, 249:336-351

  25. Roncarati, R., and Knebel-Mörsdorf, D. 1997
    Identification of the early actin rearrangement inducing factor, arif-1, from Autographa californica multicapsid nuclear polyhedrosis virus.
    J. Virol. 71, 7933-7941

  26. Murges, D., Kremer, A., and Knebel-Mörsdorf, D. 1997
    Baculovirus transactivator IE1 is functional in mammalian cells.
    J. gen. Virol. 78, 1507-1510

  27. Knebel-Mörsdorf, D. , Flipsen, J.T.M., Roncarati, R., Jahnel, F., Kleefsman, A.W.F., and Vlak, J.M. 1996
    Baculovirus infection of Spodoptera exigua larvae: LacZ expression driven by promoters of early genes pe38 and me53 in larval tissue.
    J. gen. Virol. 77, 815-824
  28. Krappa, R., Roncarati, R., and Knebel-Mörsdorf, D. 1995
    Expression of PE38 and IE2, viral members of the C3HC4 finger family, during baculovirus infection: PE38 and IE2 localize to distinct nuclear regions.
    J.Virol. 69, 5287-5293

  29. Flipsen, J.T.M., Mans, R.M.W., Knebel-Mörsdorf, D., Kleefsman, A.W.F., and Vlak, J.M. 1995
    Deletion of the baculoviral ecdysteroid UDP-glucosyltransferase gene induces early degeneration of malpighian tubules in infected insects.
    J. Virol. 69, 4529-4532

  30. Knebel-Mörsdorf, D. , Kremer, A., and Jahnel, F. 1993
    Baculovirus gene ME53, which contains a putative zinc finger motif, is one of the major early-transcribed genes.
    J. Virol. 67, 753-758.

  31. Becker, D., and Knebel-Mörsdorf, D. 1993
    Sequence and temporal appearance of the early transcribed baculovirus gene HE65.
    J. Virol. 67, 5867- 5872.

  32. Krappa, R., Behn-Krappa, A., Jahnel, F., Doerfler, W., and Knebel-Mörsdorf, D. 1992
    Differential factor binding at the promoter of early baculovirus gene PE38 during viral infection: GATA motif is recognized by an insect protein.
    J. Virol 66, 3494-3505.

  33. Krappa R., and Knebel-Mörsdorf, D. 1991
    Identification of the very early transcribed baculovirus gene PE38.
    J. Virol. 65, 805-812.


September 25, 2017
Dagmar Mörsdorf
Institute for Biochemistry II, Joseph-Stelzmann-Strasse 52, D50931 Cologne
Suggestions and wishes: Gudrun Konertz
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