Ausgewählte Publikationen
Chalovich JM, Lutz E, Baxley T, Schroeter MM (2011)
Baby SM, Bogdanovich S, Willmann G, Basu U, Lozynska O, Khurana TS (2010)
Wiesner, R (Wiesner, R.); Neuhaus, J (Neuhaus, J.); Baris, O (Baris, O.) (2010)
Eifinger, F (Eifinger, F.)1; Dercks, E (Dercks, E.)1; Roth, B (Roth, B.)1; Pfitzer, G (Pfitzer, G.)2 (2010)
Stehle R. and
Iorga B. (2010)
Kinetics of cardiac sarcomeric processes and rate-limiting steps in contraction and relaxation.
J Mol Cell Cardiol 48: 843-850, [link]
Shcherbakova
O., Serebryanaya D., Postnikov A., Schroeter M. M., Zittrich S., Noegel A. A.,
Shirinsky V., Vorotnikov A., and Pfitzer G. (2010)
Kinase related protein / telokin inhibits Ca2+-independent contraction in triton skinned guinea pig taenia coli.
Biochem J, [link]
Neppl Rl,
Lubomirov Lt, Momotani K, Pfitzer G, Eto M, and Somlyo Av, (2009)
Thromboxane A2-induced bi-directional regulation of
cerebral arterial tone.
J Biol Chem
284: 6348-6360,
[link]
Stehle R, Solzin J, Iorga B, and Poggesi C,
(2009)
Insights into the kinetics of Ca2+-regulated
contraction and relaxation from myofibril studies.
Pflugers Arch 458:
337-357,
[link]
Neulen A,
Stehle R, and Pfitzer G, (2009)
The cardiac troponin C mutation Leu29Gln found in a
patient with hypertrophic
cardiomyopathy does not alter contractile parameters in skinned murine
myocardium.
Basic Res Cardiol
104: 751-760,
[link]
Puetz S, Lubomirov Lt, and Pfitzer G, (2009)
Regulation of smooth muscle contraction by small
GTPases.
Physiology (Bethesda)
24: 342-356,
[link]
http://physiologyonline.physiology.org/
Lys184 deletion in troponin I impairs relaxation
kinetics and induces hypercontractility in murine cardiac myofibrils.
Cardiovasc Res
77: 676-686,
[link]
Kaya Z, Goser S, Buss Sj, Leuschner F, Ottl R, Li J,
Volkers M, Zittrich S, Pfitzer G, Rose Nr, and Katus Ha, (2008)
Identification of cardiac troponin I sequence motifs
leading to heart failure by induction of myocardial inflammation and fibrosis.
Circulation
118: 2063-2072,
[link]
Leuschner F, Li J, Goser S, Reinhardt L, Ottl R, Bride
P, Zehelein J, Pfitzer G, Remppis A, Giannitsis E, Katus Ha, and Kaya Z,
(2008)
Absence of auto-antibodies against cardiac troponin I
predicts improvement of left ventricular function after acute myocardial
infarction.
Eur Heart J
29: 1949-1955,
[link]
Doring B, Pfitzer G, Adam B, Liebregts T, Eckardt D,
Holtmann G, Hofmann F, Feil S, Feil R, and Willecke K, (2007)
Ablation of connexin43 in smooth muscle cells of the
mouse intestine: functional insights into physiology and morphology.
Cell Tissue Res
327: 333-342,
[link]
Iorga B, Adamek N, and Geeves Ma, (2007)
The slow skeletal muscle isoform of myosin shows
kinetic features common to smooth and non-muscle myosins.
J Biol
Chem 282: 3559-3570,
[link]
Neulen A,
Blaudeck N, Zittrich S, Metzler D, Pfitzer G, and Stehle R, (2007)
Mn2+-dependent protein phosphatase 1 enhances protein
kinase A-induced Ca2+ desensitisation in skinned murine myocardium.
Cardiovasc Res
74: 124-132,
[link]
Peche V, Shekar S, Leichter M, Korte H, Schroder R,
Schleicher M, Holak Ta, Clemen Cs, Ramanath Yb, Pfitzer G, Karakesisoglou I, and
Noegel Aa, (2007)
CAP2, cyclase-associated protein 2, is a dual
compartment protein.
Cell Mol Life Sci
64: 2702-2715,
[link]
Schaefer
A, Matthess H, Pfitzer G, and Kohle K, (2007)
[Mental health and performance of medical students with
high and low test anxiety].
Psychother Psychosom Med Psychol
57: 289-297,
[link]
Solzin J,
Iorga B, Sierakowski E, Gomez Alcazar Dp, Ruess Df, Kubacki T, Zittrich S,
Blaudeck N, Pfitzer G, and Stehle R, (2007)
Kinetic mechanism of the Ca2+-dependent switch-on and
switch-off of cardiac troponin in myofibrils.
Biophys J
93: 3917-3931,
[link]
Stehle R,
Iorga B, and Pfitzer G, (2007)
Calcium regulation of troponin and its role in the
dynamics of contraction and relaxation.
Am J Physiol Regul Integr Comp Physiol
292: R1125-1128,
[link]
Zobel C, Rana Or, Saygili E, Bolck B, Saygili E,
Diedrichs H, Reuter H, Frank K, Muller-Ehmsen J, Pfitzer G, and Schwinger Rh,
(2007)
Mechanisms of Ca2+-dependent calcineurin activation in
mechanical stretch-induced hypertrophy.
Cardiology
107: 281-290,
[link]
Goser S, Andrassy M, Buss Sj, Leuschner F, Volz Ch,
Ottl R, Zittrich S, Blaudeck N, Hardt Se, Pfitzer G, Rose Nr, Katus Ha, and Kaya
Z, (2006)
Cardiac troponin I but not cardiac troponin T induces
severe autoimmune inflammation in the myocardium.
Circulation
114: 1693-1702,
[link]
Lubomirov Lt, Reimann K, Metzler D, Hasse V, Stehle R,
Ito M, Hartshorne Dj, Gagov H, Pfitzer G, and Schubert R, (2006)
Urocortin-induced decrease in Ca2+ sensitivity of
contraction in mouse tail arteries is attributable to cAMP-dependent
dephosphorylation of MYPT1 and activation of myosin light chain phosphatase.
Circ Res
98: 1159-1167,
[link]
Lubomirov Lt, Schubert R, Gagov Hs, Duridanova Db, and
Pfitzer G, (2006)
[Urocortin decreases phosphorylation of MYPT1 and
increases the myosin phosphatase activity via elevation of the intracellular
level of cAMP].
Biofizika
51: 773-780,
[link]
Pfitzer G, Lubomirov Lt, Reimann K, Gagov H, and
Schubert R, (2006)
Regulation of the crossbridge cycle in vascular smooth
muscle by cAMP signalling.
J Muscle Res Cell Motil
27: 445-454,
[link]
Stehle R, Solzin J, Iorga B, Gomez D, Blaudeck N, and
Pfitzer G, (2006)
Mechanical properties of sarcomeres during cardiac
myofibrillar relaxation: stretch-induced cross-bridge detachment contributes to
early diastolic filling.
J Muscle Res Cell Motil
27: 423-434,
[link]
Telley Ia,
Denoth J, Stussi E, Pfitzer G, and Stehle R, (2006)
Half-sarcomere dynamics in myofibrils during activation
and relaxation studied by tracking fluorescent markers.
Biophys J
90: 514-530,
[link]
Telley Ia, Stehle R, Ranatunga Kw, Pfitzer G, Stussi E,
and Denoth J, (2006)
Dynamic behaviour of half-sarcomeres during and after
stretch in activated rabbit psoas myofibrils: sarcomere asymmetry but no 'sarcomere
popping'.
J Physiol
573: 173-185,
[link]
Wenzel D,
Schmidt A, Reimann K, Hescheler J, Pfitzer G, Bloch W, and Fleischmann Bk,
(2006)
Endostatin, the proteolytic fragment of collagen XVIII,
induces vasorelaxation.
Circ Res
98: 1203-1211,
[link]
Zhang Zg, Bothe I, Hirche F, Zweers M, Gullberg D,
Pfitzer G, Krieg T, Eckes B, and Aumailley M, (2006)
Interactions of primary fibroblasts and keratinocytes
with extracellular matrix proteins: contribution of alpha2beta1 integrin.
J Cell Sci
119: 1886-1895,
[link]
Kruger M, Zittrich S, Redwood C, Blaudeck N, James J,
Robbins J, Pfitzer G, and Stehle R, (2005)
Effects of the mutation R145G in human cardiac troponin
I on the kinetics of the contraction-relaxation cycle in isolated cardiac
myofibrils.
J Physiol
564: 347-357,
[link]
Poggesi C, Tesi C, and Stehle R, (2005)
Sarcomeric determinants of striated muscle relaxation
kinetics.
Pflugers Arch 449:
505-517,
[link]
Pfitzer G,
Schroeter M, Hasse V, Ma J, Rosgen Kh, Rosgen S, and Smyth N, (2005)
Is myosin phosphorylation sufficient to regulate smooth
muscle contraction?
Adv Exp Med Biol
565: 319-328; discussion 328, 405-315,
[link]
Klockner U, Pereverzev A, Leroy J, Krieger A, Vajna R,
Pfitzer G, Hescheler J, Malecot Co, and Schneider T, (2004)
The cytosolic II-III loop of Cav2.3 provides an
essential determinant for the phorbol ester-mediated stimulation of E-type Ca2+
channel activity.
Eur J Neurosci
19: 2659-2668,
[link]
Daub B, Schroeter M, Pfitzer G, and Ganitkevich V,
(2003)
Expression of members of the S100 Ca2+-binding protein
family in guinea-pig smooth muscle.
Cell Calcium
33: 1-10,
[link]
Gunduz D,
Hirche F, Hartel Fv, Rodewald Cw, Schafer M, Pfitzer G, Piper Hm, and Noll T,
(2003)
ATP antagonism of thrombin-induced endothelial barrier
permeability.
Cardiovasc Res
59: 470-478,
[link]
Kruger M,
Pfitzer G, and Stehle R, (2003)
Expression and purification of human cardiac troponin
subunits and their functional incorporation into isolated cardiac mouse
myofibrils.
J Chromatogr B Analyt Technol Biomed Life Sci
786: 287-296,
[link]
Leroy J, Pereverzev A, Vajna R, Qin N, Pfitzer G,
Hescheler J, Malecot Co, Schneider T, and Klockner U, (2003)
Ca2+-sensitive regulation of E-type Ca2+ channel
activity depends on an arginine-rich region in the cytosolic II-III loop.
Eur J Neurosci
18: 841-855,
[link]
Pfitzer G, Wirth A, Lucius C, Brkic-Koric D, Manser E,
De Lanerolle P, and Arner A, (2003)
Regulation of smooth muscle contraction by calcium,
monomeric GTPases of the Rho subfamily and their effector kinases.
Adv Exp Med Biol
538: 89-99; discussion 99,
[link]
Siedner S,
Kruger M, Schroeter M, Metzler D, Roell W, Fleischmann Bk, Hescheler J, Pfitzer
G, and Stehle R, (2003)
Developmental changes in contractility and sarcomeric
proteins from the early embryonic to the adult stage in the mouse heart.
J Physiol
548: 493-505,
[link]
Stehle R,
Kruger M, and Pfitzer G, (2003)
Does cross-bridge activation determine the time course
of myofibrillar relaxation?
Adv Exp Med Biol
538: 469-479; discussion 479,
[link]
Wirth A,
Schroeter M, Kock-Hauser C, Manser E, Chalovich Jm, De Lanerolle P, and Pfitzer
G, (2003)
Inhibition of contraction and myosin light chain
phosphorylation in guinea-pig smooth muscle by p21-activated kinase 1.
J Physiol
549: 489-500,
[link]
Bonnevier
J, Malmqvist U, Sonntag D, Schroeter M, Nilsson H, Pfitzer G, and Arner A,
(2002)
Sustained norepinephrine contraction in the rat portal
vein is lost when Ca(2+) is replaced with Sr(2+).
Am J Physiol Cell Physiol
282: C845-852,
[link]
Ganitkevich V, Hasse V, and Pfitzer G, (2002)
Ca2+-dependent and Ca2+-independent regulation of
smooth muscle contraction.
J Muscle Res Cell Motil
23: 47-52,
[link]
Pereverzev
A, Leroy J, Krieger A, Malecot Co, Hescheler J, Pfitzer G, Klockner U, and
Schneider T, (2002)
Alternate splicing in the cytosolic II-III loop and the
carboxy terminus of human E-type voltage-gated Ca(2+) channels:
electrophysiological characterization of isoforms.
Mol Cell Neurosci
21: 352-365,
[link]
Pereverzev
A, Vajna R, Pfitzer G, Hescheler J, Klockner U, and Schneider T, (2002)
Reduction of insulin secretion in the insulinoma cell
line INS-1 by overexpression of a Ca(v)2.3 (alpha1E) calcium channel antisense
cassette.
Eur J Endocrinol
146: 881-889,
[link]
Roell W, Lu Zj, Bloch W, Siedner S, Tiemann K, Xia Y,
Stoecker E, Fleischmann M, Bohlen H, Stehle R, Kolossov E, Brem G, Addicks K,
Pfitzer G, Welz A, Hescheler J, and Fleischmann Bk, (2002)
Cellular cardiomyoplasty improves survival after
myocardial injury.
Circulation
105: 2435-2441,
[link]
Stehle R, Kruger M, and Pfitzer G, (2002)
Force kinetics and individual sarcomere dynamics in
cardiac myofibrils after rapid ca(2+) changes.
Biophys J
83: 2152-2161,
[link]
Stehle R,
Kruger M, Scherer P, Brixius K, Schwinger Rh, and Pfitzer G, (2002)
Isometric force kinetics upon rapid activation and
relaxation of mouse, guinea pig and human heart muscle studied on the
subcellular myofibrillar level.
Basic Res Cardiol
97 Suppl 1: I127-135,
[link]
Pfitzer G, (2001)
Invited review: regulation of myosin phosphorylation in
smooth muscle.
J Appl Physiol
91: 497-503,
[link]
Pfitzer G,
Sonntag-Bensch D, and Brkic-Koric D, (2001)
Thiophosphorylation-induced Ca(2+) sensitization of
guinea-pig ileum contractility is not mediated by Rho-associated kinase.
J Physiol
533: 651-664,
[link]
Stehle R, Lionne C, Travers F, and Barman T,
(2000)
Kinetics of the initial steps of rabbit psoas
myofibrillar ATPases studied by tryptophan and pyrene fluorescence stopped-flow
and rapid flow-quench. Evidence that cross-bridge detachment is slower than ATP
binding.
Biochemistry
39: 7508-7520,
[link]
Wieneke S, Stehle R, Li Z, and Jockusch H,
(2000)
Generation of tension by skinned fibers and intact
skeletal muscles from desmin-deficient mice.
Biochem Biophys Res Commun
278: 419-425,
[link]
Arner A and Pfitzer G, (1999)
Regulation of cross-bridge cycling by Ca2+ in smooth
muscle.
Rev Physiol Biochem Pharmacol
134: 63-146,
[link]
Lucius C, Arner A, Steusloff A, Troschka M, Hofmann F,
Aktories K, and Pfitzer G, (1998)
Clostridium difficile toxin B inhibits carbachol-induced
force and myosin light chain phosphorylation in guinea-pig smooth muscle: role
of Rho proteins.
J Physiol
506 (Pt 1): 83-93,
[link]
Pfitzer G and Arner A, (1998)
Involvement of small GTPases in the regulation of
smooth muscle contraction.
Acta Physiol Scand
164: 449-456,
[link]
Wagner Kd,
Geil D, Schimke I, Stauss Hm, Lammerich A, Theres H, Pfitzer G, Vetter R, and
Gunther J, (1998)
Decreased susceptibility of contractile function to
hypoxia/reoxygenation in chronic infarcted rat hearts.
J Mol Cell Cardiol
30: 2341-2353,
[link]
Albrecht
K, Schneider A, Liebetrau C, Ruegg Jc, and Pfitzer G, (1997)
Exogenous caldesmon promotes relaxation of guinea-pig
skinned taenia coli smooth muscles: inhibition of cooperative reattachment of
latch bridges?
Pflugers Arch 434:
534-542,
[link]
Katoch Ss,
Ruegg Jc, and Pfitzer G, (1997)
Differential effects of a K+ channel agonist and Ca2+
antagonists on myosin light chain phosphorylation in relaxation of
endothelin-1-contracted tracheal smooth muscle.
Pflugers Arch
433: 472-477,
[link]
Wagner Kd, Theres H, Born A, Strube S, Wunderlich N,
Pfitzer G, Baumann G, and Gunther J, (1997)
Contractile function of papillary muscle from rats with
different infarct size after beta-adrenergic blockade and ACE-inhibition.
J Mol Cell Cardiol
29: 2941-2951,
[link]
Otto B, Steusloff A, Just I, Aktories K, and Pfitzer G,
(1996)
Role of Rho proteins in carbachol-induced contractions
in intact and permeabilized guinea-pig intestinal smooth muscle.
J Physiol
496 (Pt 2): 317-329,
[link]
Lammerich
A, Gunther J, Pfitzer G, Storch E, and Vetter R, (1995)
Alterations of cardiac contractile function are related
to changes in membrane calcium transport in spontaneously hypertensive rats.
J
Hypertens 13:
1313-1324,
[link]
Lehmann-Klose S, Beinbrech B, Cuppoletti J, Gratzl M, Ruegg Jc, and Pfitzer G,
(1995)
Ca(2+)- and GTP[gamma S]-induced translocation of the
glucose transporter, GLUT-4, to the plasma membrane of permeabilized
cardiomyocytes determined using a novel immunoprecipitation method.
Pflugers Arch
430: 333-339,
[link]
Schmidt Us, Troschka M, and Pfitzer G, (1995)
The variable coupling between force and myosin light
chain phosphorylation in Triton-skinned chicken gizzard fibre bundles: role of
myosin light chain phosphatase.
Pflugers Arch
429: 708-715,
[link]
Steusloff A, Paul E, Semenchuk La, Di Salvo J, and
Pfitzer G, (1995)
Modulation of Ca2+ sensitivity in smooth muscle by
genistein and protein tyrosine phosphorylation.
Arch
Biochem Biophys 320:
236-242,
[link]
Di Salvo J, Pfitzer G, and Semenchuk La, (1994)
Protein tyrosine phosphorylation, cellular Ca2+, and
Ca2+ sensitivity for contraction of smooth muscle.
Can J Physiol Pharmacol
72: 1434-1439,
[link]
Satoh S,
Kreutz R, Wilm C, Ganten D, and Pfitzer G, (1994)
Augmented agonist-induced Ca(2+)-sensitization of
coronary artery contraction in genetically hypertensive rats. Evidence for
altered signal transduction in the coronary smooth muscle cells.
J Clin Invest
94: 1397-1403,
[link]
Di Salvo J, Steusloff A, Semenchuk L, Satoh S, Kolquist
K, and Pfitzer G, (1993)
Tyrosine kinase inhibitors suppress agonist-induced
contraction in smooth muscle.
Biochem Biophys Res Commun
190: 968-974,
[link]
Pfitzer G, Fischer W, and Chalovich Jm, (1993)
Phosphorylation-contraction coupling in smooth muscle:
role of caldesmon.
Adv Exp Med Biol
332: 195-202; discussion 202-193,
[link]
Pfitzer G,
Zeugner C, Troschka M, and Chalovich Jm, (1993)
Caldesmon and a 20-kDa actin-binding fragment of
caldesmon inhibit tension development in skinned gizzard muscle fiber bundles.
Proc Natl Acad Sci U S A
90: 5904-5908,
[link]
Satoh S, Rensland H, and Pfitzer G, (1993)
Ras proteins increase Ca(2+)-responsiveness of smooth
muscle contraction.
FEBS Lett
324: 211-215,
[link]
Boels Pj and Pfitzer G, (1992)
Relaxant effect of phalloidin on Triton-skinned
microvascular and other smooth muscle preparations.
J Muscle Res Cell Motil
13: 71-80,
[link]
Pfitzer G,
Strauss Jd, and Ruegg Jc, (1992)
Modulation of myosin phosphorylation-contraction
coupling in skinned smooth muscle.
Jpn J Pharmacol
58 Suppl 2: 23P-28P,
[link]
Boels Pj, Troschka M, Ruegg Jc, and Pfitzer G,
(1991)
Higher Ca2+ sensitivity of triton-skinned guinea pig
mesenteric microarteries as compared with large arteries.
Circ Res
69: 989-996,
[link]
Pfitzer G
and Boels Pj, (1991)
Differential skinning of smooth muscle: a new approach
to excitation-contraction coupling.
Blood Vessels
28: 262-267,
[link]
Ruegg Jc and Pfitzer G, (1991)
Contractile protein interactions in smooth muscle.
Blood Vessels
28: 159-163,
[link]
Fischer W
and Pfitzer G, (1989)
Rapid myosin phosphorylation transients in phasic
contractions in chicken gizzard smooth muscle.
FEBS Lett
258: 59-62,
[link]
Wagner J, Pfitzer G, and Ruegg Jc, (1987)
Calcium/calmodulin activation of gizzard skinned fibers
at low levels of myosin phosphorylation.
Prog Clin Biol Res
245: 427-436,
[link]
Pfitzer G,
Merkel L, Ruegg Jc, and Hofmann F, (1986)
Cyclic GMP-dependent protein kinase relaxes skinned
fibers from guinea pig taenia coli but not from chicken gizzard.
Pflugers Arch 407:
87-91,
[link]
Pfitzer G,
Ruegg Jc, Zimmer M, and Hofmann F, (1985)
Relaxation of skinned coronary arteries depends on the
relative concentrations of Ca2+, calmodulin and active cAMP-dependent protein
kinase.
Pflugers Arch
405: 70-76,
[link]
Ruegg Jc and Pfitzer G, (1985)
Modulation of calcium sensitivity in guinea pig taenia
coli: skinned fiber studies.
Experientia
41: 997-1001,
[link]
Thomas G, Gross R, Pfitzer G, and Ruegg Jc,
(1985)
The positive inotropic dihydropyridine Bay K 8644 does
not affect calcium sensitivity or calcium release of skinned cardiac fibres.
Naunyn
Schmiedebergs Arch Pharmacol 328: 378-381,
[link]
Merkel L,
Meisheri Kd, and Pfitzer G, (1984)
The variable relation between myosin light-chain
phosphorylation and actin-activated ATPase activity in chicken gizzard smooth
muscle. Modulation by tropomyosin.
Eur J
Biochem 138:
429-434,
[link]
Pfitzer G,
Hofmann F, Disalvo J, and Ruegg Jc, (1984)
cGMP and cAMP inhibit tension development in skinned
coronary arteries.
Pflugers Arch
401: 277-280,
[link]
Pfitzer G and Ruegg Jc, (1984)
Forskolin inhibits tension development in
detergent-treated cardiac muscle fibers.
Experientia
40: 65-67,
[link]
Ruegg Jc, Kuhn Hj, Guth K, Pfitzer G, and Hofmann F,
(1984)
Tension transients in skinned muscle fibres of insect
flight muscle and mammalian cardiac muscle: effect of substrate concentration
and treatment with myosin light chain kinase.
Adv Exp Med Biol
170: 605-615,
[link]
Ruegg Jc,
Pfitzer G, Eubler D, and Zeugner C, (1984)
Effect on contractility of skinned fibres from
mammalian heart and smooth muscle by a new benzimidazole derivative,
4,5-dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methy l-3(2H)-
pyridazinone.
Arzneimittelforschung
34: 1736-1738,
[link]
Ruegg Jc,
Pfitzer G, Zimmer M, and Hofmann F, (1984)
The calmodulin fraction responsible for contraction in
an intestinal smooth muscle.
FEBS Lett
170: 383-386,
[link]
Sparrow Mp, Pfitzer G, Gagelmann M, and Ruegg Jc,
(1984)
Effect of calmodulin, Ca2+, and cAMP protein kinase on
skinned tracheal smooth muscle.
Am J
Physiol 246:
C308-314,
[link]
Ruegg Jc,
Meisheri K, Pfitzer G, and Zeugner C, (1983)
Skinned coronary smooth muscle: calmodulin, calcium
antagonists, and cAMP influence contractility.
Basic Res Cardiol
78: 462-471,
[link]
Metzger H,
Stern Ho, Pfitzer G, and Ruegg Jc, (1982)
Calcium antagonists affect calmodulin-dependent
contractility of a skinned smooth muscle.
Arzneimittelforschung
32: 1425-1427,
[link]
Pfitzer G,
Peterson Jw, and Ruegg Jc, (1982)
Length dependence of calcium activated isometric force
and immediate stiffness in living and glycerol extracted vascular smooth muscle.
Pflugers Arch 394:
174-181,
[link]
Pfitzer G,
Ruegg Jc, Flockerzi V, and Hofmann F, (1982)
cGMP-dependent protein kinase decreases calcium
sensitivity of skinned cardiac fibers.
FEBS
Lett 149: 171-175,
[link]
Herzig Jw,
Kohler G, Pfitzer G, Ruegg Jc, and Wolffle G, (1981)
Cyclic AMP inhibits contractility of detergent treated
glycerol extracted cardiac muscle.
Pflugers Arch 391:
208-212,
[link]
Pfitzer G., Peterson J.W., (1980) Stiffness of the arterial wall in response to potassium and pharmacological activation. In: Adaptability of the vascular wall. Reinis et al. (eds.) Springer Verlag Berlin, Heidelberg, New York, 125-127.
Pfitzer G., Rüegg J.C., (1984) Biochemical
regulation of the smooth muscle contraction. In: Pharmacology of the Vascular
Wall. Esplugues J. (ed.)
University Press, Valencia, 47-59.
Rüegg J.C., Sparrow M.P., Mrwa U., Schneider M., Pfitzer G., (1984) Calcium and calmodulin dependent regulatory mechanisms in chemically skinned smooth muscle. In: Smooth Muscle Contraction. Stephens N.L. (ed.) Marcel Dekker, Inc. New York, 361-372.
Rüegg J.C., Kuhn H.J., Güth K., Pfitzer G.,
Hofmann F., (1984) Tension transients in skinned muscle fibres of insect flight
muscle and mammalian cardiac muscle: effect of substrate concentration and
treatment with myosin light chain kinase. In: Contractile Mechanisms in Muscle.
Advances in Experimental Medicine and Biology. Pollack G.J. and Sugi H. (eds.)
Plenum Press, New York, London. Vol. 170, 605-615.
Rüegg J.C., Pfitzer G., (1985)
Excitation-contraction coupling in coronary smooth muscle. In: The Regulation of
Heart Function. Rupp H. (ed.)
Thieme, New York.
Pfitzer, G. und Katoch, S. (1991) Relaxation
of smooth muscle at high levels of myosin light chain (MLC) phosphorylation. In:
Cellular regulation by protein phosphorylation. Heilmeyer L.M.G., Jr (ed.).
Springer, Berlin, Heidelberg, New York, NATO/ASI Series. Series H: Cell Biology,
58, 459-464.
Boels P.J. und Pfitzer, G. (1991) Different
mechanical and biochemical properties of skinned arterioles and arteries. in:
Resistance arteries, structure and function. Mulvany, M.J. et al. (eds).
Elsevier Science Publishers Amsterdam, 77-80.
Pfitzer, G. und Rüegg, J.C. (1992) Smooth
muscle activation. In: Advances in comparative and environmental physiology Vol.
12, pp 63-86. Sugi, H. (ed).
Springer, Berlin, Heidelberg, New York
Pfitzer G. (1996) Permeabilized smooth muscle.
In: The biochemistry of smooth muscle contraction.
Barany, M (ed).
Academic press. pp 191-199.
Chalovich, J.M., and Pfitzer, G. (1997).
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