Masters module (MN-B-Gen1)

Molecular Genetics

WS 2017/18

Learning outcomes / Skills

Students who have successfully completed this module will have acquired detailed knowledge of molecular genetics and the cellular repertoire to respond to stress and environmental signals operating at different levels in the cell from gene expression to protein function and signaling.

Students will train to read and comprehend contemporary scientific literature and develop oral presentation skills. Data processing, structuring and presentation will be discussed. Furthermore, they will learn to address and solve biological problems.


Main topics:


  • genetic screens, mutant selection and gene targeting in model organisms
  • spatial control of protein localization
  • cellular stress responses such as responses to starvation, temperature, and damaging agents
  • transcriptional and post-transcriptional regulation, as well as of post-translational regulation by protein modification
  • selective ubiquitin-mediated protein degradation and degradation of abnormal proteins in yeast and mammals
  • interactions between the virus and the host cell


  • formats of scientific literature
  • searching literature databases for further reading
  • processing and presenting experimental results in written and oral form
  • preparing and structuring presentations
  • addressing and solving scientific problems


  • reading and presenting biological publications


at 9 a.m., Seminar room 0.46 (ground floor, Institute for Genetics)

Date Professor Lecture Seminar / Tutorial
04 Dec 2017 Gehring Introduction and assigning topics for the seminar    
05 - 08 Dec 2017 Lammers


Proteins (I)

Proteins (II)


Methods and their application
11 - 14 Dec 2017 Praefcke

Introduction to buffer design

Regulation of Haemostasis

Nuclear Organisation and Transport

Data mining
15 - 21 Dec 2017



Eukaryotic mRNA processing

Principles of gene expression regulation in eukaryotes

Viral strategies

Degradation of mRNAs in eukaryotes

Data presentation
08 Jan - 11 Jan 2018 Mörsdorf

Principles of virus infection (I)

Principles of virus infection (II)

Virus families (I)

Virus families (II)

Scientific presentations
12 - 17 Jan 2018 Dohmen

Control and regulation of protein function 1

Control and regulation of protein function 2

Control and regulation of protein function 3

Control and regulation of protein function 4

Solving scientific problems
18 - 23 Jan 2018



Co- and posttranscriptional control in bacteria I

Co- and posttranscriptional control in bacteria II

Co- and posttranscriptional control in bacteria II

Understanding the Publication Process
(optional 24), 25, 26 Jan 2018 ---


02 Feb 2018 ---

Written examination


Please note: no responsibility is taken for the correctness of the information included in the Seminar / Tutorial files, which were generated by the students of the module

Type of examinations

Exam prerequisites: Regular and active participation


Written examination (02nd February 2018) of topics presented and discussed during the lectures (70 % of the total module mark).

Oral presentation ([optional 24th], 25th and 26th January 2018) of a current research topic (15 min + discussion, accounts for 30 % of the total module mark).


Faculty / Contact