Group Leader

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact
Nadav Shai, Eden Yifrach, Carlo W.T. van Roermund, Laetitia Cavellini, Ramona Schuster, Lior Zada, Adam Hughes, Mafalda Escobar-Henriques, Mickael Cohen, Hans Waterham, Ronald Wanders, Maya Schuldiner and Einat Zalckvar Nature Communications in press.

Cdc48 regulates a deubiquitylase cascade critical for mitochondrial fusion
Tânia Simões, Ramona Schuster, Fabian den Brave, Mafalda Escobar-Henriques (2018) eLife 2018;7:e30015.

Mitofusins: ubiquitylation promotes fusion
M. Escobar-Henriques (2014) Cell Res, 4 387-388.

Dynamic survey of mitochondria by ubiquitin
Mafalda Escobar-Henriques and T. Langer (2014) EMBO Rep, 15(3) 231-243.

Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathway
F. Anton, G. Dittmar, T. Langer and Mafalda Escobar-Henriques (2013) Mol Cell, 49 487-498. Highlighted in Molecular Cell, in Nature Rev. Mol. Cell Biol. and in F1000.

Mechanistic perspective of mitochondrial fusion: tubulation vs. fragmentation
Mafalda Escobar-Henriques and F. Anton, (2013) BBA –Mol. Cell. Research 1833, 162-175.

Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion
F. Anton, J.M. Fres, A. Schauss, B. Pinson, G.-J. Praefcke T. Langer and Mafalda Escobar-Henriques (2011) J. Cell. Sci. 124(7), 1126-1135.

Second PostDoc

Regulation of mitochondrial fusion by the F-box protein Mdm30 involves proteasome-independent turnover of Fzo1
Mafalda Escobar-Henriques, B. Westermann and T. Langer (2006) J. Cell. Biol. 173(5), 645-650.

Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast
M. Dürr, Mafalda Escobar-Henriques, S. Merz, S. Geimer, T. Langer and B. Westermann (2006) Mol. Biol. Cell 17(9), 3745-3755.

Mitochondrial shaping cuts
Mafalda Escobar-Henriques and T. Langer (2006) BBA –Mol. Cell. Research 1763(5-6), 422-429.

First PostDoc

The critical cis-acting element required for IMD2 feedback regulation by GDP is a TATA box located 202 nucleotides upstream of the transcription start site
Mafalda Escobar-Henriques, B. Daignan-Fornier and M. A. Collart (2003)Mol. Cell. Biol. 1763(17), 6267-6278.

Transcription initiation of the yeast IMD2 gene is abolished in response to nutrient limitation through a sequence in its coding region
Mafalda Escobar-Henriques, M. A. Collart and B. Daignan-Fornier (2003) Mol. Cell. Biol. 23(17):6279-90.


Proteome analysis and morphological studies reveal multiple effects of the immunosuppressive drug mycophenolic acid specifically resulting from guanylic nucleotide depletion
Mafalda Escobar-Henriques, A. Balguerie, C. Monribot, H. Boucherie and B. Daignan-Fornier (2001) J Biol Chem. 276, 46237-46242.

Transcriptional regulation of the yeast gmp synthesis pathway by its end products
Mafalda Escobar-Henriques and B. Daignan-Fornier (2001) J Biol Chem. 276, 1523-1530.